4-Pentenoicacid,2-amino-2-methyl-,methylester(9CI)

Base Information

• Chemical Name: 4-Pentenoicacid,2-amino-2-methyl-,methylester(9CI)
• CAS No.: 120963-07-7
• Molecular Formula: C₇H₁₃NO₂
• Molecular Weight: 143.186
• Mol file: 120963-07-7.mol

Synonyms:

Chemical Property of 4-Pentenoicacid,2-amino-2-methyl-,methylester(9CI)

Chemical Property:

Purity/Quality:

≥95% ^*data from raw suppliers

(R)-2-Amino-2-methyl-pent-4-enoicAcidMethylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Pentenoicacid,2-amino-2-methyl-,methylester(9CI)

There total 1 articles about 4-Pentenoicacid,2-amino-2-methyl-,methylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + Cα-methyl-D,L-allylglycinamide (144125-67-7) → C7H13NO2 (120963-07-7)

Guidance literature:

With thionyl chloride; In methanol; for 17h; Heating;

DOI:10.1002/adsc.200600446

Reference yield:

p-toluenesulfonyl chloride (98-59-9) + C7H13NO2 (120963-07-7) → DL-Ts-α-methyl-α-allylglycine-OMe

Guidance literature:

With trimethylamine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1002/ejoc.201600896

Reference yield:

C7H13NO2 (120963-07-7) → C17H21NO4S (1402405-67-7)

Guidance literature:

Multi-step reaction with 2 steps

1: trimethylamine / dichloromethane / 0 - 20 °C

2: sodium hydride / 0 - 20 °C

With sodium hydride; trimethylamine; In dichloromethane;

DOI:10.1002/ejoc.201600896

upstream raw materials:

methanol

C^α-methyl-D,L-allylglycinamide

Downstream raw materials:

C₁₇H₂₁NO₄S

Refernces