Pyrrolidine, 3-methyl-1-phenyl-

Base Information

• Chemical Name: Pyrrolidine, 3-methyl-1-phenyl-
• CAS No.: 106027-38-7
• Molecular Formula: C11H15N
• Molecular Weight: 161.247
• Mol file: 106027-38-7.mol

Synonyms:

Chemical Property of Pyrrolidine, 3-methyl-1-phenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pyrrolidine, 3-methyl-1-phenyl-

There total 10 articles about Pyrrolidine, 3-methyl-1-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

carbon monoxide (201230-82-2) + N-(2-methylallyl)aniline (22774-81-8) → N-phenyl-3-methylpyrrolidine (106027-38-7)

Guidance literature:

With sodium tetrahydroborate; η⁶-C6H6BPh3^-Rh(COD)⁺; In dichloromethane; isopropyl alcohol; at 100 ℃; for 30h; under 26220 Torr;

DOI:10.1021/jo00038a019

Reference yield: 75.0%

methyl 2-methylsuccinate (21307-96-0,22644-27-5,63163-08-6,1604-11-1) + aniline (62-53-3) → N-phenyl-3-methylpyrrolidine (106027-38-7)

Guidance literature:

With methanesulfonic acid; hydrogen; tris(acetylacetonato)ruthenium(III); [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine]; In 1,4-dioxane; at 220 ℃; for 3h; under 7500.75 Torr;

DOI:10.1039/c7sc01718a

Reference yield: 60.0%

Allyl-(2-iodo-ethyl)-phenyl-amine → N-phenyl-3-methylpyrrolidine (106027-38-7)

Guidance literature:

With manganese; In tetrahydrofuran; at 25 ℃;

DOI:10.1055/s-1998-1897

upstream raw materials:

carbon monoxide

N-(2-methylallyl)aniline

N-methylaniline

methyl 2-methylsuccinate