(2R,3R)-2,3-cis-3-acetoxy-8-<(2R,3R,4R)-2,3-cis-3,4-trans-3-acetoxy-3',4',5,7-tetramethoxyflavan-4-yl>-3',4',5,7-tetramethoxyflavan

Base Information

• Chemical Name: (2R,3R)-2,3-cis-3-acetoxy-8-<(2R,3R,4R)-2,3-cis-3,4-trans-3-acetoxy-3',4',5,7-tetramethoxyflavan-4-yl>-3',4',5,7-tetramethoxyflavan
• CAS No.: 3888-39-9
• Molecular Formula: C₄₂H₄₆O₁₄
• Molecular Weight: 774.819
• Mol file: 3888-39-9.mol

Synonyms:

Chemical Property of (2R,3R)-2,3-cis-3-acetoxy-8-<(2R,3R,4R)-2,3-cis-3,4-trans-3-acetoxy-3',4',5,7-tetramethoxyflavan-4-yl>-3',4',5,7-tetramethoxyflavan

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3R)-2,3-cis-3-acetoxy-8-<(2R,3R,4R)-2,3-cis-3,4-trans-3-acetoxy-3',4',5,7-tetramethoxyflavan-4-yl>-3',4',5,7-tetramethoxyflavan

There total 8 articles about (2R,3R)-2,3-cis-3-acetoxy-8-<(2R,3R,4R)-2,3-cis-3,4-trans-3-acetoxy-3',4',5,7-tetramethoxyflavan-4-yl>-3',4',5,7-tetramethoxyflavan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic anhydride (108-24-7) + 5,7,3',4',5'',7'',3''',4'''-octa-O-methylprocyanidin B-3 (37126-92-4) → octa-O-methyl-di-O-acetyl-bis-(+)-catechin (3888-39-9,7700-79-0,14617-31-3,17941-25-2,17947-27-2,28699-22-1,41093-86-1,67253-07-0,67253-08-1,97233-63-1)

Guidance literature:

In pyridine;

DOI:10.1039/P19810001235

Reference yield:

5,7,3',4'-tetra-O-methylepicatechin (51196-02-2) → (2R,3R)-2,3-cis-3-acetoxy-8-<(2R,3R,4R)-2,3-cis-3,4-trans-3-acetoxy-3',4',5,7-tetramethoxyflavan-4-yl>-3',4',5,7-tetramethoxyflavan (3888-39-9,7700-79-0,14617-31-3,17941-25-2,17947-27-2,28699-22-1,41093-86-1,67253-07-0,67253-08-1,97233-63-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 310 mg / Pb(OAc)2 / benzene / 28 h / Ambient temperature

2: 1.) 0.1M HCl / 1.) EtOH, 24 h, 2.) MeOH, Et₂O, -15 deg C, 48 h

3: pyridine

With pyridine; hydrogenchloride; lead acetate; In benzene;

Reference yield:

5,7,3',4'-tetra-O-methylepicatechin-4β,8-(5,7,3',4'-tetra-O-methylepicatechin) (37064-32-7) + acetic anhydride (108-24-7) → (2R,3R)-2,3-cis-3-acetoxy-8-<(2R,3R,4R)-2,3-cis-3,4-trans-3-acetoxy-3',4',5,7-tetramethoxyflavan-4-yl>-3',4',5,7-tetramethoxyflavan (3888-39-9,7700-79-0,14617-31-3,17941-25-2,17947-27-2,28699-22-1,41093-86-1,67253-07-0,67253-08-1,97233-63-1)

Guidance literature:

With pyridine; Yield given;

upstream raw materials:

acetic anhydride

diazomethane

4β-methoxy-tetra-O-methyl-3-O-acetyl-(-)-epicatechin

catechin