Technology Process of 1,2-Bis(1-ethoxyethoxy)-4-methoxybenzene
There total 1 articles about 1,2-Bis(1-ethoxyethoxy)-4-methoxybenzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
trichloroacetic acid;
In
dichloromethane;
for 96h;
Yield given;
Ambient temperature;
DOI:10.1021/jo00065a015
- Guidance literature:
-
Multi-step reaction with 10 steps
2: aq. NaOH / dimethylformamide / 60 °C
3: aq. NaOH / ethanol; dioxane / 1) 80 deg C, 5 h, 2) rt, overnight
4: SOCl2, DMF / toluene / 1.5 h / 60 °C
5: CH2Cl2
6: 85 percent / H2 / 5percent Pd/C / ethanol / 760 Torr
7: DMAP, pyridine / CHCl3 / 18 h / Ambient temperature
8: Br2, pyridine / CHCl3 / 5 h
9: aq. HCl / tetrahydrofuran / 3 h / 80 °C
10: methanol
With
pyridine; hydrogenchloride; dmap; sodium hydroxide; thionyl chloride; hydrogen; bromine; N,N-dimethyl-formamide;
palladium on activated charcoal;
In
tetrahydrofuran; 1,4-dioxane; methanol; ethanol; dichloromethane; chloroform; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jo00065a015
- Guidance literature:
-
Multi-step reaction with 9 steps
2: aq. NaOH / dimethylformamide / 60 °C
3: aq. NaOH / ethanol; dioxane / 1) 80 deg C, 5 h, 2) rt, overnight
4: SOCl2, DMF / toluene / 1.5 h / 60 °C
5: CH2Cl2
6: 85 percent / H2 / 5percent Pd/C / ethanol / 760 Torr
7: DMAP, pyridine / CHCl3 / 18 h / Ambient temperature
8: Br2, pyridine / CHCl3 / 5 h
9: aq. HCl / tetrahydrofuran / 3 h / 80 °C
With
pyridine; hydrogenchloride; dmap; sodium hydroxide; thionyl chloride; hydrogen; bromine; N,N-dimethyl-formamide;
palladium on activated charcoal;
In
tetrahydrofuran; 1,4-dioxane; ethanol; dichloromethane; chloroform; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jo00065a015
