2-(4-Chlorophenyl)-3,6-dimethylpyrano[4,3-c]pyrazol-4(2H)-one

Base Information

Chemical Name:2-(4-Chlorophenyl)-3,6-dimethylpyrano[4,3-c]pyrazol-4(2H)-one
CAS No.:106089-52-5
Molecular Formula:C14H11ClN2O2
Molecular Weight:274.707
Hs Code.:
ChEMBL ID:CHEMBL1951952
DSSTox Substance ID:DTXSID80544376

Synonyms:106089-52-5;2-(4-Chlorophenyl)-3,6-dimethylpyrano[4,3-c]pyrazol-4(2H)-one;CHEMBL1951952;DTXSID80544376

Suppliers and Price of 2-(4-Chlorophenyl)-3,6-dimethylpyrano[4,3-c]pyrazol-4(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-Chlorophenyl)-3,6-dimethylpyrano[4,3-c]pyrazol-4(2H)-one

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:274.0509053
Heavy Atom Count:19
Complexity:404

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=NN(C(=C2C(=O)O1)C)C3=CC=C(C=C3)Cl

Technology Process of 2-(4-Chlorophenyl)-3,6-dimethylpyrano[4,3-c]pyrazol-4(2H)-one

There total 3 articles about 2-(4-Chlorophenyl)-3,6-dimethylpyrano[4,3-c]pyrazol-4(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 83516-81-8
3-acetyl-4-chloro-6-methyl-2H-pyran-2-one

: 1073-69-4
N-4-chlorophenylhydrazine

: 106089-52-5
2-(4-chlorophenyl)-3,6-dimethylpyrano<4,3-c>pyrazol-4(2H)-one

Guidance literature:: With acetic acid; Reflux;
DOI:10.1016/j.ejmech.2012.01.042

Reference yield: 83.0%

: 1073-70-7
4-chlorophenylhydrazine hydrochloride

4-chloro-3-(1-chlorovinyl)-6-methyl-2-pyrone: 106089-51-4
4-chloro-3-(1-chlorovinyl)-6-methyl-2-pyrone

: 106089-52-5
2-(4-chlorophenyl)-3,6-dimethylpyrano<4,3-c>pyrazol-4(2H)-one

Guidance literature:: With sodium acetate; In methanol; for 91h; Heating;
DOI:10.1246/cl.1986.295

Reference yield:

: 771-03-9
3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one

: 106089-52-5
2-(4-chlorophenyl)-3,6-dimethylpyrano<4,3-c>pyrazol-4(2H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 33 percent / phosphoryl chloride / 4.5 h / Heating

2: 83 percent / methanol / 91 h / Heating

With trichlorophosphate; In methanol;
DOI:10.1246/bcsj.60.4425