(+)-deoxyschizandrin

Base Information

• Chemical Name: (+)-deoxyschizandrin
• CAS No.: 101757-58-8
• Molecular Formula: C₂₄H₃₂O₆
• Molecular Weight: 416.514
• Mol file: 101757-58-8.mol

Synonyms:

Chemical Property of (+)-deoxyschizandrin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-deoxyschizandrin

There total 41 articles about (+)-deoxyschizandrin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

5,5'-(2,3-dimethylbutane-1,4-diyl)bis(1,2,3-trimethoxybenzene) (50544-08-6,72730-20-2,75597-96-5,115587-61-6,107191-91-3) → (+/-)-deoxyschizandrin (61281-38-7,63598-55-0,63640-13-1,69176-53-0,101757-58-8,114488-89-0,115587-63-8,115587-64-9,157087-43-9,157087-44-0)

Guidance literature:

With vanadium(V) oxytrifluoride; trifluoroacetic acid; In dichloromethane; 1) -78 deg C, 30 min, 2) room temperature, 30 min;

Reference yield: 25.0%

1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-5,8-dihydrodibenzocyclooctene → schisandrin A (156769-17-4) + (+/-)-1,2,3,10,11,12-hexamethoxy-r-6,t-7-dimethyl-5,6,7,8-tetrahydrodibenzocyclooctene (61281-38-7,63598-55-0,63640-13-1,69176-53-0,101757-58-8,114488-89-0,115587-63-8,115587-64-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 24h;

Reference yield:

elemicin (487-11-6) → (+/-)-deoxyschizandrin (61281-38-7,63598-55-0,63640-13-1,69176-53-0,101757-58-8,114488-89-0,115587-63-8,115587-64-9,157087-43-9,157087-44-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 70 percent / HBr / acetic acid / 3 h / 0 °C

2: 1) Mg, 2) (E)-2-t-butyl-3-phenyloxaziridine / 1) THF, 0 deg C, 2) 0 deg C, 15 h

3: 56 percent / trifluoroacetic acid, VOF₃ / CH₂Cl₂ / 1) -78 deg C, 30 min, 2) room temperature, 30 min

With 2-tert-butyl-3-phenyloxaziridine; vanadium(V) oxytrifluoride; hydrogen bromide; magnesium; trifluoroacetic acid; In dichloromethane; acetic acid;

upstream raw materials:

5,5'-(2,3-dimethylbutane-1,4-diyl)bis(1,2,3-trimethoxybenzene)

elemicin

1-(3,4,5-trimethoxyphenyl)-2-bromopropane

(2R,3R)-2,3-dimethyl-1,4-bis(3,4,5-trimethoxyphenyl)butane

Downstream raw materials:

(-)-gomisin J