Technology Process of 1-[4-(2,5-dioxopyrrolidine-1-yl)benzenesulphonyl]-5-oxopyrrolidine-2-carboxylic acid amide
There total 6 articles about 1-[4-(2,5-dioxopyrrolidine-1-yl)benzenesulphonyl]-5-oxopyrrolidine-2-carboxylic acid amide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: chlorosulfonic acid / 2 h / 80 - 85 °C
2: dmap; sodium carbonate / 2 h
3: acetyl chloride / benzene / 4 h / 100 °C
4: thionyl chloride / 2 h / 20 °C / Inert atmosphere
5: dmap; ammonia / benzene / 1 h / Inert atmosphere
With
chlorosulfonic acid; dmap; thionyl chloride; ammonia; sodium carbonate; acetyl chloride;
In
benzene;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: dmap; sodium carbonate / 2 h
2: acetyl chloride / benzene / 4 h / 100 °C
3: thionyl chloride / 2 h / 20 °C / Inert atmosphere
4: dmap; ammonia / benzene / 1 h / Inert atmosphere
With
dmap; thionyl chloride; ammonia; sodium carbonate; acetyl chloride;
In
benzene;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: acetyl chloride / benzene / 4 h / 100 °C
2: thionyl chloride / 2 h / 20 °C / Inert atmosphere
3: dmap; ammonia / benzene / 1 h / Inert atmosphere
With
dmap; thionyl chloride; ammonia; acetyl chloride;
In
benzene;
