1-benzyl-4-methyl-1,4-dihydronicotinamide

Base Information

• Chemical Name: 1-benzyl-4-methyl-1,4-dihydronicotinamide
• CAS No.: 19355-10-3
• Molecular Formula: C₁₄H₁₆N₂O
• Molecular Weight: 228.294
• Mol file: 19355-10-3.mol

Synonyms:

Chemical Property of 1-benzyl-4-methyl-1,4-dihydronicotinamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-benzyl-4-methyl-1,4-dihydronicotinamide

There total 9 articles about 1-benzyl-4-methyl-1,4-dihydronicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

1-benzyl-3-carbamoylpyridinium ion (16183-83-8) → 1-Benzyl-6-methyl-1,6-dihydro-pyridine-3-carboxylic acid amide (123743-71-5) + 1-Benzyl-2-methyl-1,2-dihydro-pyridine-3-carboxylic acid amide (123743-75-9) + 1-benzyl-4-methyl-1,4-dihydronicotinamide (19355-10-3)

Guidance literature:

In acetonitrile; at 24.9 ℃;

Reference yield: 51.0%

1-benzyl-3-carbamoylpyridinium ion (16183-83-8) → 1-Benzyl-6-methyl-1,6-dihydro-pyridine-3-carboxylic acid amide (123743-71-5) + 1-Benzyl-2-methyl-1,2-dihydro-pyridine-3-carboxylic acid amide (123743-75-9) + 1-benzyl-4-methyl-1,4-dihydronicotinamide (19355-10-3)

Guidance literature:

With trans-<(CH3)2Co(DpnH)>; In acetonitrile; at 24.9 ℃; Rate constant;

Reference yield:

1-benzyl-3-carbamoyl-4-methylpyridinium bromide (22109-42-8) → 1-benzyl-4-methyl-1,4-dihydronicotinamide (19355-10-3) + 1-benzyl-4-methyl-1,6-dihydronicotinamide

Guidance literature:

With sodium dithionite; sodium hydrogencarbonate; In chloroform; water; at 4 - 5 ℃; for 3h; Title compound not separated from byproducts;

DOI:10.1016/j.tet.2005.07.096

upstream raw materials:

1-benzyl-3-carbamoylpyridinium ion

1-Benzyl-1,4-dihydronicotinamide

1-benzyl-4-methyl-3-carbamoylpyridinium

3-(aminocarbonyl)-1-(phenylmethyl)pyridinium perchlorate

Downstream raw materials:

9,10-dihydro-10-methylacridine

9-(4'-methoxyphenyl)-9H-xanthene

1-Benzyl-1,4-dihydronicotinamide