C₂₆H₂₅FN₄O

Base Information

Chemical Name:C₂₆H₂₅FN₄O
CAS No.:1175013-26-9
Molecular Formula:C₂₆H₂₅FN₄O
Molecular Weight:428.509
Hs Code.:

C<sub>26</sub>H<sub>25</sub>FN<sub>4</sub>O

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₆H₂₅FN₄O

Chemical Property:

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Technology Process of C₂₆H₂₅FN₄O

There total 6 articles about C₂₆H₂₅FN₄O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1175015-18-5
4-[2-(3-fluoro-2-methyl-benzyl)-1-phenyl-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-piperazine-1-carboxylic acid tert-butyl ester

: 1175013-26-9
C₂₆H₂₅FN₄O

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃;
DOI:10.1016/j.bmcl.2011.06.112

Reference yield:

: 1-phenyl-1H-pyrrolo[2,3-b]pyridine

: 1175013-26-9
C₂₆H₂₅FN₄O

Guidance literature:: Multi-step reaction with 5 steps

1.1: bromine / water; tert-butyl alcohol / 20 °C

1.2: 20 °C

2.1: sodium dihydrogenphosphate; sodium chlorite / tert-butyl alcohol / 20 °C

3.1: 4-methyl-morpholine; O-<[cyano(ethoxycarbonyl)methylene]amino>-1,1,3,3-tetramethyluronium tetrafluoroborate / N,N-dimethyl-formamide / 20 °C

4.1: zinc / tetrahydrofuran / 0 °C

4.2: -78 - 20 °C

4.3: 100 °C

5.1: trifluoroacetic acid / dichloromethane / 20 °C

With 4-methyl-morpholine; sodium chlorite; sodium dihydrogenphosphate; O-<[cyano(ethoxycarbonyl)methylene]amino>-1,1,3,3-tetramethyluronium tetrafluoroborate; bromine; trifluoroacetic acid; zinc; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; tert-butyl alcohol; 1.1: Vilsmeier-Haack formylation;
DOI:10.1016/j.bmcl.2011.06.112

Reference yield:

: 847801-39-2
2-chloro-1-phenyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde

: 1175013-26-9
C₂₆H₂₅FN₄O

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium dihydrogenphosphate; sodium chlorite / tert-butyl alcohol / 20 °C

2.1: 4-methyl-morpholine; O-<[cyano(ethoxycarbonyl)methylene]amino>-1,1,3,3-tetramethyluronium tetrafluoroborate / N,N-dimethyl-formamide / 20 °C

3.1: zinc / tetrahydrofuran / 0 °C

3.2: -78 - 20 °C

3.3: 100 °C

4.1: trifluoroacetic acid / dichloromethane / 20 °C

With 4-methyl-morpholine; sodium chlorite; sodium dihydrogenphosphate; O-<[cyano(ethoxycarbonyl)methylene]amino>-1,1,3,3-tetramethyluronium tetrafluoroborate; trifluoroacetic acid; zinc; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1016/j.bmcl.2011.06.112