Phosphoric acid (2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 5-chloro-quinolin-8-yl ester

Base Information

Chemical Name:Phosphoric acid (2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 5-chloro-quinolin-8-yl ester
CAS No.:80824-68-6
Molecular Formula:C₃₁H₃₆Cl₂N₃O₈PSi
Molecular Weight:708.607
Hs Code.:

Phosphoric acid (2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 5-chloro-quinolin-8-yl ester

Synonyms:

Suppliers and Price of Phosphoric acid (2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 5-chloro-quinolin-8-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Phosphoric acid (2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 5-chloro-quinolin-8-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Phosphoric acid (2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 5-chloro-quinolin-8-yl ester

There total 3 articles about Phosphoric acid (2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 5-chloro-quinolin-8-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 80817-47-6
Phosphoric acid benzotriazol-1-yl ester (2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester

: 130-16-5
5-Chloro-8-hydroxyquinoline

: 80824-68-6
Phosphoric acid (2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 5-chloro-quinolin-8-yl ester

Guidance literature:: With 1-methyl-1H-imidazole; In tetrahydrofuran; for 1h;
DOI:10.1016/S0040-4039(01)91336-X

Reference yield:

: 80817-46-5
bis(benzotriazol-1-yl)(2-chlorophenyl)phosphate

: 80824-68-6
Phosphoric acid (2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 5-chloro-quinolin-8-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 0.5 h / 20 °C

2: 64 percent / N-methylimidazole / tetrahydrofuran / 1 h

With 1-methyl-1H-imidazole; In tetrahydrofuran;
DOI:10.1016/S0040-4039(01)91336-X

Reference yield:

: 15074-54-1
2-chlorophenyl dichlorophosphate

: 80824-68-6
Phosphoric acid (2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 5-chloro-quinolin-8-yl ester

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / tetrahydrofuran / 1 h / 20 °C

2: tetrahydrofuran / 0.5 h / 20 °C

3: 64 percent / N-methylimidazole / tetrahydrofuran / 1 h

With pyridine; 1-methyl-1H-imidazole; In tetrahydrofuran;
DOI:10.1016/S0040-4039(01)91336-X