80817-46-5

Basic information

• Product Name: bis(benzotriazol-1-yl)(2-chlorophenyl)phosphate
• Synonyms: bis(benzotriazol-1-yl)(2-chlorophenyl)phosphate
• CAS NO: 80817-46-5
• Molecular Weight: 442.758
• Mol File: 80817-46-5.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: bis(benzotriazol-1-yl)(2-chlorophenyl)phosphate(CAS DataBase Reference)
• NIST Chemistry Reference: bis(benzotriazol-1-yl)(2-chlorophenyl)phosphate(80817-46-5)
• EPA Substance Registry System: bis(benzotriazol-1-yl)(2-chlorophenyl)phosphate(80817-46-5)

Safety Data

• Hazardous Substances Data: 80817-46-5(Hazardous Substances Data)

Upstream product

• 2592-95-2 benzotriazol-1-ol 
• 15074-54-1 2-chlorophenyl dichlorophosphate 

Downstream Products

• 89291-52-1 Hexadecanoic acid (S)-2-[(benzotriazol-1-yloxy)-(2-chloro-phenoxy)-phosphoryloxy]-1-hexadecanoyloxymethyl-ethyl ester 
• 78098-94-9 C₆₄H₆₅Cl₂N₁₁O₁₇P₂ 
• 139036-69-4 Phosphoric acid benzotriazol-1-yl ester (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-{4-[2-(tert-butyl-diphenyl-silanyloxymethyl)-benzoylamino]-2-oxo-2H-pyrimidin-1-yl}-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 
• 139052-29-2 Phosphoric acid benzotriazol-1-yl ester (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-{6-[2-(tert-butyl-diphenyl-silanyloxymethyl)-benzoylamino]-purin-9-yl}-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 
• 131796-96-8 C₁₅₉H₁₅₅Cl₂N₃O₃₁P₂ 
• 89291-57-6 4-Oxo-pentanoic acid (2R,3S,5R)-2-[(benzotriazol-1-yloxy)-(2-chloro-phenoxy)-phosphoryloxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 
• 103627-70-9 Phosphoric acid benzotriazol-1-yl ester (2R,3R,3aR,9aR)-2-(6-benzoylamino-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl ester 2-chloro-phenyl ester 
• 82507-05-9 Acetic acid (R)-2-[(benzotriazol-1-yloxy)-(2-chloro-phenoxy)-phosphoryloxy]-1-hexadecyloxymethyl-ethyl ester 
• 111716-86-0 C₁₃₁H₁₅₈Cl₂N₂O₂₉P₂Si₃ 
• 95331-60-5 C₆₀H₆₆Cl₂N₈O₂₄P₂S 
• 110744-83-7 C₈₇H₈₆ClN₆O₂₂P 
• 110744-84-8 C₁₂₄H₁₂₁Cl₂N₁₁O₃₂P₂ 
• 81803-03-4 Acetic acid (2R,3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-{2-[(2-chloro-phenoxy)-hydroxy-phosphoryloxy]-3-[(4-methoxy-phenyl)-diphenyl-methoxy]-propoxy}-tetrahydro-pyran-3-yl ester 
• 91592-80-2 Phosphoric acid benzotriazol-1-yl ester (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(2-diphenylacetylamino-6-oxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 

Relevant articles and documents

Preparation of a disulfide-linked precipitative soluble support for solution-phase synthesis of trimeric oligodeoxyribonucleotide 3-(2-chlorophenylphosphate) building blocks

The preparation of a disulfide-tethered precipitative soluble support and its use for solution-phase synthesis of tnmenc oligodeoxy-ribonucleotide 3′-(2-chlorophenylphosphate) building blocks is described. To obtain the building blocks, N-acyl protected 2

New approach for the synthesis of c-di-GMP and its analogues

The synthesis of cyclic bis(3′-5′)diguanylic acid (c-di-GMP) by using a new flexible approach is reported. The flexibility of the method is exemplified by the synthesis of base-modified analogues that will find applications in the elucidation of c-di-GMP

A convenient method for the preparation of terminal methyl phosphates of nucleic acids

The reagent 2-chlorophenyl bis(1-benzotriazolyl) phosphate has been used for the preparation of 5'-O-(methyl phosphate) esters of the dimers TpT, UpU, Upm62A and m62ApU, as well as 3',5'-bis-O-(methyl phosphate)esters of uridine (U)