[(fac-1,1-bis(2-pyridyl)phenylethane(-1H))Pd(tert-butyl isocyanide)(4-MeC₆H₄)(trifluoromethyl)]OTf

Base Information

• Chemical Name: [(fac-1,1-bis(2-pyridyl)phenylethane(-1H))Pd(tert-butyl isocyanide)(4-MeC₆H₄)(trifluoromethyl)]OTf
• CAS No.: 1346257-58-6
• Molecular Formula: CF₃O₃S*C₃₁H₃₁F₃N₃Pd
• Molecular Weight: 758.093
• Mol file: 1346257-58-6.mol

Synonyms:

Chemical Property of [(fac-1,1-bis(2-pyridyl)phenylethane(-1H))Pd(tert-butyl isocyanide)(4-MeC₆H₄)(trifluoromethyl)]OTf

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [(fac-1,1-bis(2-pyridyl)phenylethane(-1H))Pd(tert-butyl isocyanide)(4-MeC₆H₄)(trifluoromethyl)]OTf

There total 2 articles about [(fac-1,1-bis(2-pyridyl)phenylethane(-1H))Pd(tert-butyl isocyanide)(4-MeC₆H₄)(trifluoromethyl)]OTf which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

tert-butylisonitrile (119072-55-8,7188-38-7) + [(fac-1,1-bis(2-pyridyl)phenylethane(-1H))PdCl(4-MeC6H4)(trifluoromethyl)] (1346257-56-4) + silver trifluoromethanesulfonate (2923-28-6) → [(fac-1,1-bis(2-pyridyl)phenylethane(-1H))Pd(tert-butyl isocyanide)(4-MeC6H4)(trifluoromethyl)]OTf (1346257-58-6)

Guidance literature:

In dichloromethane; byproducts: AgCl; Sonication; (N2); sonication of suspn. of (C6H4C(Me)(C5H4N)2)Pd(4-MeC6H4)(CF3)Cl andAgCF3SO3 in CH2Cl2 for 15 min at room temp., filtration, addn. of tert- butyl isocyanide, stirring for 3 min; removal of volatiles under reduced pressure, suspending in Et2O, filtration, washing with Et2O, drying under reduced pressure;

DOI:10.1021/om200779j

Reference yield:

1-fluoro-2,4,6-trimethylpyridinium trifluoromethanesulfonate (107264-00-6) → [(fac-1,1-bis(2-pyridyl)phenylethane(-1H))Pd(tert-butyl isocyanide)(4-MeC6H4)(trifluoromethyl)]OTf (1346257-58-6)

Guidance literature:

Multi-step reaction with 2 steps

1: brine / dichloromethane

2: dichloromethane

With brine; In dichloromethane;

DOI:10.1021/om200779j

upstream raw materials:

tert-butylisonitrile

[(fac-1,1-bis(2-pyridyl)phenylethane(-1H))PdCl(4-MeC₆H₄)(trifluoromethyl)]

silver trifluoromethanesulfonate

1-fluoro-2,4,6-trimethylpyridinium trifluoromethanesulfonate