ester de tert-butylique de l'acide (acetoxy methyl)-3(<<(amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2>-acetyl>-amino)-7 β cepheme-3 carboxylique-4

Base Information

• Chemical Name: ester de tert-butylique de l'acide (acetoxy methyl)-3(<<(amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2>-acetyl>-amino)-7 β cepheme-3 carboxylique-4
• CAS No.: 68672-63-9
• Molecular Formula: C₄₀H₄₀N₆O₈S₂
• Molecular Weight: 796.925
• Mol file: 68672-63-9.mol

Synonyms:

Chemical Property of ester de tert-butylique de l'acide (acetoxy methyl)-3(<<(amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2>-acetyl>-amino)-7 β cepheme-3 carboxylique-4

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ester de tert-butylique de l'acide (acetoxy methyl)-3(<<(amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2>-acetyl>-amino)-7 β cepheme-3 carboxylique-4

There total 4 articles about ester de tert-butylique de l'acide (acetoxy methyl)-3(<<(amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2>-acetyl>-amino)-7 β cepheme-3 carboxylique-4 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(ethoxy-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle (68672-60-6) → ester de tert-butylique de l'acide (acetoxy methyl)-3(<<(amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2>-acetyl>-amino)-7 β cepheme-3 carboxylique-4 (68672-63-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 90 percent / sodium hydroxide / dioxane / 1 h / Ambient temperature

2: 93 percent / isobutyl chloroformate, N-methylmorpholine, ammonia / tetrahydrofuran / -20 °C

3: 40 percent / sodium hydroxide / dioxane / 3 h / Ambient temperature

4: 41 percent / dicyclohexylcarbodiimide / CH₂Cl₂ / 2 h

With 4-methyl-morpholine; sodium hydroxide; ammonia; dicyclohexyl-carbodiimide; isobutyl chloroformate; In tetrahydrofuran; 1,4-dioxane; dichloromethane;

Reference yield:

(amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle (68672-61-7) → ester de tert-butylique de l'acide (acetoxy methyl)-3(<<(amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2>-acetyl>-amino)-7 β cepheme-3 carboxylique-4 (68672-63-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 40 percent / sodium hydroxide / dioxane / 3 h / Ambient temperature

2: 41 percent / dicyclohexylcarbodiimide / CH₂Cl₂ / 2 h

With sodium hydroxide; dicyclohexyl-carbodiimide; In 1,4-dioxane; dichloromethane;

Reference yield:

(carboxy methoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle (73599-77-6) → ester de tert-butylique de l'acide (acetoxy methyl)-3(<<(amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2>-acetyl>-amino)-7 β cepheme-3 carboxylique-4 (68672-63-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 93 percent / isobutyl chloroformate, N-methylmorpholine, ammonia / tetrahydrofuran / -20 °C

2: 40 percent / sodium hydroxide / dioxane / 3 h / Ambient temperature

3: 41 percent / dicyclohexylcarbodiimide / CH₂Cl₂ / 2 h

With 4-methyl-morpholine; sodium hydroxide; ammonia; dicyclohexyl-carbodiimide; isobutyl chloroformate; In tetrahydrofuran; 1,4-dioxane; dichloromethane;

upstream raw materials:

(amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle

(carboxy methoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle

(ethoxy-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle

ethyl (Z)-2-(2-triphenylmethylaminothiazol-4-yl)-2-(hydroxyimino)acetate hydrochloride