4-(2-Methyl-5-oxooxazol-4-ylidenemethyl)benzonitrile

Base Information

Chemical Name:4-(2-Methyl-5-oxooxazol-4-ylidenemethyl)benzonitrile
CAS No.:43229-82-9
Molecular Formula:C₁₂H₈N₂O₂
Molecular Weight:212.208
Hs Code.:
DSSTox Substance ID:DTXSID101194455

Synonyms:SCHEMBL5634085;DTXSID101194455;4-(4'-cyanobenzylidene)-2-methyl-5(4h)-oxazolone;4-(2-Methyl-5-oxooxazol-4-ylidenemethyl)benzonitrile;4-[(2-Methyl-5-oxo-4(5H)-oxazolylidene)methyl]benzonitrile;4-[(2-methyl-5-oxo-4,5-dihydro-1,3-oxazol-4-ylidene)methyl]benzonitrile;43229-82-9

Suppliers and Price of 4-(2-Methyl-5-oxooxazol-4-ylidenemethyl)benzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(2-Methyl-5-oxooxazol-4-ylidenemethyl)benzonitrile

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:212.058577502
Heavy Atom Count:16
Complexity:406

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=NC(=CC2=CC=C(C=C2)C#N)C(=O)O1

Technology Process of 4-(2-Methyl-5-oxooxazol-4-ylidenemethyl)benzonitrile

There total 4 articles about 4-(2-Methyl-5-oxooxazol-4-ylidenemethyl)benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 105-07-7
4-cyanobenzaldehyde

: 543-24-8
N-acetylglycine

: 94929-80-3,43229-82-9
4-(2-methyl-5-oxo-oxazol-4-ylidenemethyl)-benzonitrile

Guidance literature:: With sodium acetate; acetic anhydride; at 95 - 135 ℃; for 6h;
DOI:10.1016/j.tet.2012.04.102

Reference yield:

: 105-07-7
4-cyanobenzaldehyde

: 43229-82-9,94929-80-3
2-Methyl-4-(4-cyanbenzyliden)-oxazolinon-5

Guidance literature:: Multi-step reaction with 2 steps

1: sodium acetate / acetic anhydride / 100 - 110 °C

2: acetonitrile / Irradiation

With sodium acetate; In acetic anhydride; acetonitrile;
DOI:10.1016/j.tet.2013.09.009