4-(3,4,5-trimethoxyphenyl)butyl methanesulphonate

Base Information

• Chemical Name: 4-(3,4,5-trimethoxyphenyl)butyl methanesulphonate
• CAS No.: 102222-57-1
• Molecular Formula: C₁₄H₂₂O₆S
• Molecular Weight: 318.391
• Mol file: 102222-57-1.mol

Synonyms:

Chemical Property of 4-(3,4,5-trimethoxyphenyl)butyl methanesulphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(3,4,5-trimethoxyphenyl)butyl methanesulphonate

There total 4 articles about 4-(3,4,5-trimethoxyphenyl)butyl methanesulphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(3,4,5-trimethoxy-phenyl)-butyric acid (5101-01-9) → 4-(3,4,5-trimethoxyphenyl)butyl methanesulphonate (102222-57-1)

Guidance literature:

Multi-step reaction with 2 steps

1: borane-dimethyl sulphide / diethyl ether / 1 h / Heating

2: Et₃N / diethyl ether / 3 h / Ambient temperature

With dimethylsulfide borane complex; triethylamine; In diethyl ether;

DOI:10.1016/S0040-4020(01)96619-0

Reference yield:

4-(3,4,5-trimethoxyphenyl)butan-1-ol (87797-23-7) + methanesulfonyl chloride (124-63-0) → 4-(3,4,5-trimethoxyphenyl)butyl methanesulphonate (102222-57-1)

Guidance literature:

With triethylamine;

DOI:10.1016/S0040-4039(00)81480-X

Reference yield:

3,4,5-trimethoxycinnamic acid (90-50-6) → 4-(3,4,5-trimethoxyphenyl)butyl methanesulphonate (102222-57-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 54 percent

2: 92 percent / KOH / ethanol; H₂O / 3 h / Heating

3: borane-dimethyl sulphide / diethyl ether / 1 h / Heating

4: Et₃N / diethyl ether / 3 h / Ambient temperature

With potassium hydroxide; dimethylsulfide borane complex; triethylamine; In diethyl ether; ethanol; water;

DOI:10.1016/S0040-4020(01)96619-0

upstream raw materials:

4-(3,4,5-trimethoxyphenyl)butan-1-ol

methanesulfonyl chloride

3,4,5-trimethoxycinnamic acid

4-(3,4,5-trimethoxy-phenyl)-butyric acid

Downstream raw materials:

4-(3,4,5-trimethoxyphenyl)butyl triphenylphosphonium bromide

1-(4-methoxyphenyl)-6,7,8-trimethoxytetralin

5-[4-(4,4-Dimethoxy-cyclohexa-2,5-dienylidene)-butyl]-1,2,3-trimethoxy-benzene

4-(3,4,5-trimethoxyphenyl)butyl bromide