4-Chlorobenzyl 4-bromophenyl ketone

Base Information

• Chemical Name: 4-Chlorobenzyl 4-bromophenyl ketone
• CAS No.: 107028-33-1
• Molecular Formula: C14H10BrClO
• Molecular Weight: 309.59
• DSSTox Substance ID: DTXSID00558096
• Wikidata: Q82440248
• Mol file: 107028-33-1.mol

Synonyms:107028-33-1;4-CHLOROBENZYL 4-BROMOPHENYL KETONE;1-(4-Bromophenyl)-2-(4-chlorophenyl)ethanone;SCHEMBL6201625;4-Chlorobenzyl4-bromophenylketone;DTXSID00558096;LUDVLJKIERZORX-UHFFFAOYSA-N;AKOS006037660;(4-Bromophenyl)-(4-chlorobenzyl)-ketone;1-(4-Bromophenyl)-2-(4-chlorophenyl)ethan-1-one

Chemical Property of 4-Chlorobenzyl 4-bromophenyl ketone

Chemical Property:

• XLogP3: 4.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 307.96036
• Heavy Atom Count: 17
• Complexity: 253

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1CC(=O)C2=CC=C(C=C2)Br)Cl

Technology Process of 4-Chlorobenzyl 4-bromophenyl ketone

There total 7 articles about 4-Chlorobenzyl 4-bromophenyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

3-(4-bromo-phenyl)-2-(4-chloro-phenyl)-3-oxo-propionaldehyde → 1-(4-bromophenyl)-2-(4-chlorophenyl)ethanone (107028-33-1)

Guidance literature:

With ethylenediamine; In tetrahydrofuran; for 3h; Heating;

DOI:10.1080/00397910601130967

Reference yield: 71.3%

4-chlorophenylacetic Acid (1878-66-6) + bromobenzene (108-86-1,52753-63-6) → 1-(4-bromophenyl)-2-(4-chlorophenyl)ethanone (107028-33-1)

Guidance literature:

With aluminum (III) chloride; thionyl chloride; at 0 - 20 ℃; for 0.75h;

Reference yield: 55.0%

bromobenzene (108-86-1,52753-63-6) + 4-chlorophenacetyl chloride (25026-34-0) → 1-(4-bromophenyl)-2-(4-chlorophenyl)ethanone (107028-33-1)

Guidance literature:

With aluminium trichloride;

upstream raw materials:

bromobenzene

4-chlorophenacetyl chloride

4-chlorophenylacetic Acid

(4-bromophenyl)(3-(4-chlorophenyl)oxiran-2-yl)methanone

Downstream raw materials:

N-(1-(4-bromophenyl)-2-(4-chlorophenyl)ethyl)-4-methoxyaniline

N-(1-(4-bromophenyl)-2-(4-chlorophenyl)ethylidene)-4-methoxyaniline