ethyl 3-(2-ethoxy-2-oxoethoxy)picolinate

Base Information

• Chemical Name: ethyl 3-(2-ethoxy-2-oxoethoxy)picolinate
• CAS No.: 107095-98-7
• Molecular Formula: C12H15NO5
• Molecular Weight: 253.25100
• Hs Code.: 2933399090
• Mol file: 107095-98-7.mol

Synonyms:3-ethoxycarbonylmethoxypyridine-2-carboxylic acid ethyl ester;

Chemical Property of ethyl 3-(2-ethoxy-2-oxoethoxy)picolinate

Chemical Property:

• PSA: 74.72000
• LogP: 1.20020
• Storage Temp.: 2-8°C

Purity/Quality:

95+% ^*data from raw suppliers

Ethyl3-(2-ethoxy-2-oxoethoxy)picolinate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 3-(2-ethoxy-2-oxoethoxy)picolinate

There total 3 articles about ethyl 3-(2-ethoxy-2-oxoethoxy)picolinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

ethyl 3-hydroxypyridine-2-carboxylate (73406-50-5) + ethyl bromoacetate (105-36-2) → ethyl 2-(2-ethoxycarbonyl-3-pyridyloxy)acetate (107095-98-7)

Guidance literature:

With potassium carbonate; In acetone; for 15h; Heating;

Reference yield:

3-hydroxypyridine-2-carboxylic acid (874-24-8) → ethyl 2-(2-ethoxycarbonyl-3-pyridyloxy)acetate (107095-98-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / sulfuric acid / benzene / 40 h / Heating

2: 84 percent / K₂CO₃ / acetone / 15 h / Heating

With sulfuric acid; potassium carbonate; In acetone; benzene;

Reference yield:

→ ethyl 2-(2-ethoxycarbonyl-3-pyridyloxy)acetate (107095-98-7)

Guidance literature:

upstream raw materials:

ethyl 3-hydroxypyridine-2-carboxylate

ethyl bromoacetate

3-hydroxypyridine-2-carboxylic acid

Downstream raw materials:

3-hydroxy-2,3-dihydrofuro<3,2-b>pyridine

furo[3,2-b]pyridine

ethyl 3-hydroxyfuro<3,2-b>pyridine-2-carboxylate