1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxothieno<2,3-d>pyrimidine-6-carboxaldehyde phenylhydrazone

Base Information

• Chemical Name: 1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxothieno<2,3-d>pyrimidine-6-carboxaldehyde phenylhydrazone
• CAS No.: 129177-44-2
• Molecular Formula: C₁₅H₁₄N₄O₂S
• Molecular Weight: 314.368
• Mol file: 129177-44-2.mol

Synonyms:

Chemical Property of 1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxothieno<2,3-d>pyrimidine-6-carboxaldehyde phenylhydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxothieno<2,3-d>pyrimidine-6-carboxaldehyde phenylhydrazone

There total 3 articles about 1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxothieno<2,3-d>pyrimidine-6-carboxaldehyde phenylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

6-formyl-1,3-dimethylthieno<2,3-d>pyrimidine-2,4(1H,3H)-dione (129177-38-4) + phenylhydrazine (100-63-0) → 1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxothieno<2,3-d>pyrimidine-6-carboxaldehyde phenylhydrazone (129177-44-2)

Guidance literature:

In methanol; for 0.25h; Heating;

DOI:10.1002/jhet.5570270345

Reference yield:

1,3-dimethylthieno<2,3-d>pyrimidine-2,4(1H,3H)-dione (129177-37-3) → 1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxothieno<2,3-d>pyrimidine-6-carboxaldehyde phenylhydrazone (129177-44-2)

Guidance literature:

Multi-step reaction with 2 steps

1: POCl₃ / 1 h / 95 - 100 °C

2: 43 percent / methanol / 0.25 h / Heating

With trichlorophosphate; In methanol;

DOI:10.1002/jhet.5570270345

Reference yield:

1,3-dimethyl-6-sulfanylpyrimidine-2,4(1H,3H)dione → 1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxothieno<2,3-d>pyrimidine-6-carboxaldehyde phenylhydrazone (129177-44-2)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium acetate / H₂O / Ambient temperature

2: POCl₃ / 1 h / 95 - 100 °C

3: 43 percent / methanol / 0.25 h / Heating

With sodium acetate; trichlorophosphate; In methanol; water;

DOI:10.1002/jhet.5570270345

upstream raw materials:

6-formyl-1,3-dimethylthieno<2,3-d>pyrimidine-2,4(1H,3H)-dione

phenylhydrazine

1,3-dimethylthieno<2,3-d>pyrimidine-2,4(1H,3H)-dione