1-(3-Bromophenyl)cyclobutanol

Base Information

• Chemical Name: 1-(3-Bromophenyl)cyclobutanol
• CAS No.: 210826-67-8
• Molecular Formula: C₁₀H₁₁BrO
• Molecular Weight: 227.101
• European Community (EC) Number: 976-420-1
• Mol file: 210826-67-8.mol

Synonyms:210826-67-8;1-(3-Bromophenyl)cyclobutanol;1-(3-Bromophenyl)-cyclobutanol;1-(3-BROMOPHENYL)CYCLOBUTAN-1-OL;SCHEMBL7144286;1-(3-bromo-phenyl)cyclobutanol;1-(3-Bromo-phenyl)-cyclobutanol;ABDSPZIVLQFVPF-UHFFFAOYSA-N;MFCD23708969;AKOS027425782;AB90569;DB-200941;CS-0194273;EN300-197190

Chemical Property of 1-(3-Bromophenyl)cyclobutanol

Chemical Property:

• Boiling Point: 318.2±25.0 °C(Predicted)
• PKA: 14.41±0.20(Predicted)
• Density: 1.547±0.06 g/cm3(Predicted)
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 225.99933
• Heavy Atom Count: 12
• Complexity: 165

Purity/Quality:

99% ^*data from raw suppliers

1-(3-Bromophenyl)cyclobutan-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CC(C1)(C2=CC(=CC=C2)Br)O

Technology Process of 1-(3-Bromophenyl)cyclobutanol

There total 1 articles about 1-(3-Bromophenyl)cyclobutanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

cyclobutanone (1191-95-3) + 1,3-dibromobenzene (108-36-1) → 1-(3-bromophenyl)cyclobutan-1-ol (210826-67-8)

Guidance literature:

1,3-dibromobenzene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.5h;

cyclobutanone; In tetrahydrofuran; at -78 ℃;

DOI:10.1055/s-2004-825611

Reference yield: 86.0%

1-(3-bromophenyl)cyclobutan-1-ol (210826-67-8) → 1-bromo-3-cyclobutylbenzene (17789-13-8)

Guidance literature:

With triethylsilane; boron trifluoride diethyl etherate; In dichloromethane; at -70 ℃; for 2h; Inert atmosphere;

Reference yield: 57.0%

1-(3-bromophenyl)cyclobutan-1-ol (210826-67-8) → 5-(3-bromophenyl)-3,4-dihydro-2H-pyrrole (374589-00-1)

Guidance literature:

With ferric(III) bromide; O-(methylsulfonyl)hydroxylammonium trifluoromethanesulfonate; In acetonitrile; at 20 ℃; for 6h;

DOI:10.1021/acs.orglett.1c04304

upstream raw materials:

cyclobutanone

1,3-dibromobenzene

Downstream raw materials:

1-bromo-3-cyclobutylbenzene

5-(3-bromophenyl)-3,4-dihydro-2H-pyrrole

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 210826-67-8 1-(3-Bromophenyl)-cyclobutanol

Send

Send

Metric Ton KG G Pound L ML

Send

Send