(2S,3R)-2-hydroxy-3-methylbutanedioic acid

Base Information Edit

Chemical Name:(2S,3R)-2-hydroxy-3-methylbutanedioic acid
CAS No.:85026-06-8
Molecular Formula:C₅H₈O₅
Molecular Weight:148.116
Hs Code.:
European Community (EC) Number:816-607-6
Metabolomics Workbench ID:57551
Nikkaji Number:J2.134.503B
Wikidata:Q27122234
Mol file:85026-06-8.mol

Synonyms:(2S,3R)-2-hydroxy-3-methylbutanedioic acid;85026-06-8;L-erythro-3-methylmalic acid;(2S,3R)-2-hydroxy-3-methylsuccinic acid;SCHEMBL2249094;CHEBI:50787;NPYQJIHHTGFBLN-GBXIJSLDSA-N;(2S,3R)-2-hydroxy-3-methylbutanedioicacid;EN300-1087078;Q27122234

Suppliers and Price of (2S,3R)-2-hydroxy-3-methylbutanedioic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (2S,3R)-2-hydroxy-3-methylbutanedioic acid Edit

Chemical Property:

XLogP3:-0.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:148.03717335
Heavy Atom Count:10
Complexity:152

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C(C(=O)O)O)C(=O)O
Isomeric SMILES:C[C@H]([C@@H](C(=O)O)O)C(=O)O

Technology Process of (2S,3R)-2-hydroxy-3-methylbutanedioic acid

There total 12 articles about (2S,3R)-2-hydroxy-3-methylbutanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 50460-80-5,64864-56-8,73889-80-2,77398-86-8,78512-74-0,89104-81-4,150024-71-8,73890-17-2
(2S,3R)-2-Hydroxy-3-methylbernsteinsaeure-dimethylester

: 85026-06-8,5380-36-9,5380-37-0
(2S,3R)-3-methylmalic acid

Guidance literature:: (2S,3R)-2-Hydroxy-3-methylbernsteinsaeure-dimethylester; With potassium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 24h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; methanol; water; pH=1;
DOI:10.1002/anie.200906311

Reference yield:

: (S,S)-diisopropyl tartrate

: 874646-33-0
diisopropyl (2R,3S)-2-methyl-3-hydroxybutanedioate

: 13398-41-9,5380-36-9,5380-37-0
(2S, 3S)-threo-β-methylmalic acid

: 85026-06-8,5380-36-9,5380-37-0
(2S,3R)-3-methylmalic acid

Guidance literature:: (S,S)-diisopropyl tartrate; diisopropyl (2R,3S)-2-methyl-3-hydroxybutanedioate; With potassium hydroxide; water; In tetrahydrofuran; at 0 - 20 ℃; for 48h;

With hydrogenchloride; In water;