Propanamide, N,N'-1,2-phenylenebis[2-hydroxy-2-methyl-

Base Information

• Chemical Name: Propanamide, N,N'-1,2-phenylenebis[2-hydroxy-2-methyl-
• CAS No.: 107680-76-2
• Molecular Formula: C14H20N2O4
• Molecular Weight: 280.324
• Mol file: 107680-76-2.mol

Synonyms:

Chemical Property of Propanamide, N,N'-1,2-phenylenebis[2-hydroxy-2-methyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Propanamide, N,N'-1,2-phenylenebis[2-hydroxy-2-methyl-

There total 1 articles about Propanamide, N,N'-1,2-phenylenebis[2-hydroxy-2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1,2-bis(2-(trimethylacetoxy)-2-methylpropanamido)benzene (107680-80-8) → 1,2-bis-(2-hydroxy-2-methylpropanamido)benzene (107680-76-2)

Guidance literature:

With sodium hydroxide; In methanol; ethanol; for 3h; Heating;

DOI:10.1021/ja00244a020

Reference yield: 53.0%

copper(II) acetate monohydrate (6046-93-1) + tetraphenyl phosphonium chloride (2001-45-8) + 1,2-bis-(2-hydroxy-2-methylpropanamido)benzene (107680-76-2) → P(C6H5)4(1+)*{Cu(OC(CH3)2CONC6H4NCOC(CH3)2O)}(1-)*2H2O={P(C6H5)4}{Cu(C14H16N2O4)}*2H2O

Guidance literature:

With NaOH; AgOOCCH₃; In ethanol; Cu(OAc)2*H2O, ligand, and NaOH were stirred in ethanol (1h); addn. of solid AgOAc; filtration through Celite; removal of solvent; dissolution in ethanol and further oxidation with AgOAc; removal of solvent; dissolution in H2O and addn. of (PPh4)Cl;; recrystn. from acetone/water; elem. anal.;;

DOI:10.1021/ja00244a020

Reference yield:

cobalt(II) acetate (71-48-7,917-69-1,5931-89-5,55881-15-7,68931-68-0,68931-69-1,93029-27-7) + tetraphenyl phosphonium chloride (2001-45-8) + 1,2-bis-(2-hydroxy-2-methylpropanamido)benzene (107680-76-2) → P(C6H5)4(1+)*{Co((OC(CH3)2CON)2C6H4)}(1-)*2H2O=(P(C6H5)4){Co(OC(CH3)2CON)2C6H4}*2H2O (100909-71-5)

Guidance literature:

With H₂O; NaOH; In ethanol; Co(O2CCH3)2 reacted with 1 equiv. of ligand and excess NaOH in EtOH under air; (PPh4)Cl added; recrystd. from H2O; elem. anal.;

DOI:10.1021/ja00268a058

upstream raw materials:

1,2-bis(2-(trimethylacetoxy)-2-methylpropanamido)benzene

Downstream raw materials:

P(C₆H₅)4⁽¹⁺⁾*{Co((OC(CH₃)2CON)2C₆H₄)}^(1-)*2H₂O=(P(C₆H₅)4){Co(OC(CH₃)2CON)2C₆H₄}*2H₂O