Technology Process of C15H12FN5O
There total 3 articles about C15H12FN5O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3-(1H-tetrazol-5-yl)benzoic acid;
With
pyridine; chloro-trimethyl-silane;
In
toluene;
Inert atmosphere;
With
thionyl chloride; N,N-dimethyl-formamide;
for 2h;
Inert atmosphere;
Reflux;
(3-fluorophenyl)methanamine;
With
pyridine;
In
toluene;
Inert atmosphere;
Reflux;
DOI:10.1002/cmdc.201200334
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydroxide / methanol; water / Inert atmosphere
2.1: pyridine; chloro-trimethyl-silane / toluene / Inert atmosphere
2.2: 2 h / Inert atmosphere; Reflux
2.3: Inert atmosphere; Reflux
With
pyridine; chloro-trimethyl-silane; sodium hydroxide;
In
methanol; water; toluene;
2.3: |Schotten-Baumann Reaction;
DOI:10.1002/cmdc.201200334
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium azide; ammonium chloride / N,N-dimethyl-formamide / Inert atmosphere
2.1: sodium hydroxide / methanol; water / Inert atmosphere
3.1: pyridine; chloro-trimethyl-silane / toluene / Inert atmosphere
3.2: 2 h / Inert atmosphere; Reflux
3.3: Inert atmosphere; Reflux
With
pyridine; chloro-trimethyl-silane; sodium azide; ammonium chloride; sodium hydroxide;
In
methanol; water; N,N-dimethyl-formamide; toluene;
3.3: |Schotten-Baumann Reaction;
DOI:10.1002/cmdc.201200334
