Technology Process of methyl 2,7-diacetamido-4-O-benzyl-2,3,7-trideoxy-6-O-mesyl-α-D-allo-heptopyranoside
There total 7 articles about methyl 2,7-diacetamido-4-O-benzyl-2,3,7-trideoxy-6-O-mesyl-α-D-allo-heptopyranoside which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 99 percent / 60 percent sodium hydride, tetrabutylammonium iodide / dimethylformamide / 1.5 h / Ambient temperature
2: 85 percent / p-toluenesulfonic acid / methanol / 1 h
3: 1.) pyridine, phosphoric acid, dicyclohexylcarbodiimide; 2.) oxalic acid / 1.) DMSO, benzene, 2 h, rt; 2.) methanol
4: 1 M sodium methoxide / methanol
5: 1.) hydrogen / 1.) Raney nickel / 1.) methanol
6: 96 percent / pyridine
7: sodium acetate, acetic anhydride / H2O; methanol / reflux, 15 h; 1 h
8: 90 percent / pyridine
With
pyridine; phosphoric acid; hydrogen; sodium methylate; sodium acetate; oxalic acid; acetic anhydride; tetra-(n-butyl)ammonium iodide; sodium hydride; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide;
nickel;
In
methanol; water; N,N-dimethyl-formamide;
DOI:10.1246/bcsj.60.1529
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 99 percent / 60 percent sodium hydride, tetrabutylammonium iodide / dimethylformamide / 1.5 h / Ambient temperature
2: 85 percent / p-toluenesulfonic acid / methanol / 1 h
3: 1.) pyridine, phosphoric acid, dicyclohexylcarbodiimide; 2.) oxalic acid / 1.) DMSO, benzene, 2 h, rt; 2.) methanol
4: 1 M sodium methoxide / methanol
5: 1.) hydrogen / 1.) Raney nickel / 1.) methanol
6: 96 percent / pyridine
7: sodium acetate, acetic anhydride / H2O; methanol / reflux, 15 h; 1 h
8: 90 percent / pyridine
With
pyridine; phosphoric acid; hydrogen; sodium methylate; sodium acetate; oxalic acid; acetic anhydride; tetra-(n-butyl)ammonium iodide; sodium hydride; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide;
nickel;
In
methanol; water; N,N-dimethyl-formamide;
DOI:10.1246/bcsj.60.1529
