2-((5-Methoxy-2-nitrophenyl)amino)ethanol

Base Information

• Chemical Name: 2-((5-Methoxy-2-nitrophenyl)amino)ethanol
• CAS No.: 78213-34-0
• Molecular Formula: C9H12 N2 O4
• Molecular Weight: 212.205
• DSSTox Substance ID: DTXSID50228858
• Wikidata: Q83108939
• Mol file: 78213-34-0.mol

Synonyms:2-((5-Methoxy-2-nitrophenyl)amino)ethanol;Ethanol, 2-((5-methoxy-2-nitrophenyl)amino)-;78213-34-0;SCHEMBL10580319;DTXSID50228858;TXKCTQZGCPFJCM-UHFFFAOYSA-N;AKOS019021760

Chemical Property of 2-((5-Methoxy-2-nitrophenyl)amino)ethanol

Chemical Property:

• Vapor Pressure: 1.92E-08mmHg at 25°C
• Boiling Point: 437.9°C at 760 mmHg
• Flash Point: 218.7°C
• Density: 1.336g/cm³
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 212.07970687
• Heavy Atom Count: 15
• Complexity: 207

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C(C=C1)[N+](=O)[O-])NCCO

Technology Process of 2-((5-Methoxy-2-nitrophenyl)amino)ethanol

There total 3 articles about 2-((5-Methoxy-2-nitrophenyl)amino)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

2-bromo-4-methoxy-1-nitrobenzene (98447-30-4) + ethanolamine (141-43-5) → 1-(2-hydroxyethyl)-5-methoxy-2-nitroaniline (78213-34-0)

Guidance literature:

at 50 ℃; for 64h;

Reference yield: 73.0%

ethanolamine (141-43-5) + 3-chloro-4-nitroanisole (28987-59-9) → 1-(2-hydroxyethyl)-5-methoxy-2-nitroaniline (78213-34-0)

Guidance literature:

at 50 ℃; for 4h;

DOI:10.1039/b806883f

Reference yield:

→ 1-(2-hydroxyethyl)-5-methoxy-2-nitroaniline (78213-34-0)

Guidance literature:

3-Chlor-4-nitro-anisol, 2-Amino-aethanol, Butanol, Sieden;

DOI:10.1039/jr9630004763

upstream raw materials:

ethanolamine

3-chloro-4-nitroanisole

2-bromo-4-methoxy-1-nitrobenzene

Downstream raw materials:

2-((2-amino-5-methoxyphenyl)amino)ethanol

2-(2-aminoethyl)-1-(2-hydroxyethyl)-6-methoxybenzimidazole dihydrochloride

2-(6-methoxy-1H-benzo[d]imidazol-1-yl)ethanol