Boc-4-bromo-D-phenylalanine ethyl ester

Base Information

Chemical Name:Boc-4-bromo-D-phenylalanine ethyl ester
CAS No.:1047975-40-5
Molecular Formula:C₁₆H₂₂BrNO₄
Molecular Weight:372.259
Hs Code.:
Mol file:1047975-40-5.mol

Synonyms:

Suppliers and Price of Boc-4-bromo-D-phenylalanine ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Activate Scientific
Boc-4-bromo-D-phenylalanine ethyl ester 95% ee
5 g
$ 774.00

Activate Scientific
Boc-4-bromo-D-phenylalanine ethyl ester 95% ee
1 g
$ 247.00

Acrotein
Boc-4-bromo-D-phenylalanineethylester 97%
1g
$ 183.33

Total 5 raw suppliers

Chemical Property of Boc-4-bromo-D-phenylalanine ethyl ester

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Boc-4-bromo-D-phenylalanine ethyl ester 95% ee ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Boc-4-bromo-D-phenylalanine ethyl ester

There total 1 articles about Boc-4-bromo-D-phenylalanine ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 75-03-6
ethyl iodide

: 62129-39-9,79561-82-3
4-bromo-N-{[(1,1-dimethylethyl)oxy]carbonyl}-L-phenylalanine

: 591249-54-6,1047975-40-5
ethyl (S)-3-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)propanoate

Guidance literature:: With sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 20 ℃; for 24h; Inert atmosphere;
DOI:10.1002/anie.201602908

Reference yield:

: 591249-54-6,1047975-40-5
ethyl (S)-3-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)propanoate

: (S)-2-((tert-butoxycarbonyl)amino)-3-(4-(3,5-dimethylisoxazol-4-yl)phenyl)propanoicacid

Guidance literature:: Multi-step reaction with 2 steps

1: palladium diacetate; ruphos; sodium carbonate / ethanol / 24 h / 100 °C / Sealed tube; Inert atmosphere

2: lithium hydroxide / water; methanol; tetrahydrofuran

With palladium diacetate; sodium carbonate; lithium hydroxide; ruphos; In tetrahydrofuran; methanol; ethanol; water;
DOI:10.1002/anie.201602908

Reference yield:

: 591249-54-6,1047975-40-5
ethyl (S)-3-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)propanoate

: (S)-2-amino-3-(4-(3,5-dimethylisoxazol-4-yl)phenyl)propanoic acid hydrochloride

: C₁₄H₁₆N₂O₃*ClH

Guidance literature:: Multi-step reaction with 3 steps

1: palladium diacetate; ruphos; sodium carbonate / ethanol / 24 h / 100 °C / Sealed tube; Inert atmosphere

2: lithium hydroxide / water; methanol; tetrahydrofuran

3: hydrogenchloride / water; diethyl ether / 30 h / 20 °C

With hydrogenchloride; palladium diacetate; sodium carbonate; lithium hydroxide; ruphos; In tetrahydrofuran; methanol; diethyl ether; ethanol; water;
DOI:10.1002/anie.201602908