Glycine, N-[(phenylmethoxy)carbonyl]-, cyclohexyl ester

Base Information

• Chemical Name: Glycine, N-[(phenylmethoxy)carbonyl]-, cyclohexyl ester
• CAS No.: 108977-05-5
• Molecular Formula: C16H21NO4
• Molecular Weight: 291.347
• Mol file: 108977-05-5.mol

Synonyms:

Chemical Property of Glycine, N-[(phenylmethoxy)carbonyl]-, cyclohexyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Glycine, N-[(phenylmethoxy)carbonyl]-, cyclohexyl ester

There total 3 articles about Glycine, N-[(phenylmethoxy)carbonyl]-, cyclohexyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methyl N-benzyloxycarbonylglycinate (1212-53-9) + cyclohexanol (108-93-0) → glycine N-carboxy-N-benzyl cyclohexyl ester (108977-05-5)

Guidance literature:

With Zn₄(OCOCF₃)6O; In di-isopropyl ether; for 18h; Heating;

DOI:10.1021/jo800625v

Reference yield: 76.0%

N-(Benzyloxycarbonyl)glycine (1138-80-3) + cyclohexanol (108-93-0) → glycine N-carboxy-N-benzyl cyclohexyl ester (108977-05-5)

Guidance literature:

With N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; In chloroform; for 12h; Ambient temperature;

DOI:10.1021/jo00126a080

Reference yield:

2-benzyloxycarbonylamino-acetimidic acid cyclohexyl ester; hydrochloride → glycine N-carboxy-N-benzyl cyclohexyl ester (108977-05-5)

Guidance literature:

With water;

upstream raw materials:

N-(Benzyloxycarbonyl)glycine

cyclohexanol

methyl N-benzyloxycarbonylglycinate

Downstream raw materials:

N-(carbobenzyloxy)glycinamide

glycine cyclohexyl ester