Cyclopentanone, 3-(dimethylphenylsilyl)-

Base Information

• Chemical Name: Cyclopentanone, 3-(dimethylphenylsilyl)-
• CAS No.: 109023-10-1
• Molecular Formula: C13H18OSi
• Molecular Weight: 218.371
• DSSTox Substance ID: DTXSID20446466
• Nikkaji Number: J1.059.161I
• Mol file: 109023-10-1.mol

Synonyms:109023-10-1;3-(Dimethyl(phenyl)silyl)cyclopentanone;Cyclopentanone, 3-(dimethylphenylsilyl)-;DTXSID20446466;3-(Dimethylphenylsilyl)cyclopentanone

Chemical Property of Cyclopentanone, 3-(dimethylphenylsilyl)-

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 218.112691728
• Heavy Atom Count: 15
• Complexity: 241

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C1CCC(=O)C1)C2=CC=CC=C2

Technology Process of Cyclopentanone, 3-(dimethylphenylsilyl)-

There total 5 articles about Cyclopentanone, 3-(dimethylphenylsilyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

cyclopent-2-enone (930-30-3) + dimethyl(phenyl)silyllithium (3839-31-4) → 3-(dimethyl(phenyl)silyl)cyclopentanone (109023-10-1)

Guidance literature:

With copper(I) iodide dimethyl sulfide complex; In tetrahydrofuran; at -78 - 0 ℃; for 11h;

DOI:10.1021/jo048269e

Reference yield: 92.0%

cyclopent-2-enone (930-30-3) + dimethylphenyl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)silane (185990-03-8) → 3-(dimethyl(phenyl)silyl)cyclopentanone (109023-10-1)

Guidance literature:

With [2,2]bipyridinyl; copper carbonate hydroxide; In water; at 20 ℃; for 12h;

DOI:10.1002/jccs.201700186

Reference yield: 91.0%

cyclopent-2-enone (930-30-3) + 1,2-diphenyltetramethyldisilane (1145-98-8) → 3-(dimethyl(phenyl)silyl)cyclopentanone (109023-10-1)

Guidance literature:

With copper(I) trifluoromethanesulfonate benzene; tributylphosphine; In N,N-dimethyl-formamide; at 80 ℃; for 24h;

DOI:10.1021/ja9822557

upstream raw materials:

cyclopent-2-enone

1,1-dichloro-1-phenyl-2,2,2-trimethyldisilane

dimethyl(phenyl)silyllithium

1,2-diphenyltetramethyldisilane

Downstream raw materials:

[Dimethyl-(3-trimethylsilanyloxy-cyclopent-2-enyl)-silanyl]-benzene

[Dimethyl-(3-trimethylsilanyloxy-cyclopent-3-enyl)-silanyl]-benzene