Phenol, 2-methoxy-4-(methoxymethyl)-3-methyl-

Base Information

Chemical Name:Phenol, 2-methoxy-4-(methoxymethyl)-3-methyl-
CAS No.:109685-13-4
Molecular Formula:C10H14O3
Molecular Weight:182.219
Hs Code.:
DSSTox Substance ID:DTXSID80461195
Wikidata:Q82285466
Mol file:109685-13-4.mol

Synonyms:109685-13-4;Phenol, 2-methoxy-4-(methoxymethyl)-3-methyl-;SCHEMBL12143330;DTXSID80461195

Suppliers and Price of Phenol, 2-methoxy-4-(methoxymethyl)-3-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Phenol, 2-methoxy-4-(methoxymethyl)-3-methyl-

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:182.094294304
Heavy Atom Count:13
Complexity:149

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C=CC(=C1OC)O)COC

Technology Process of Phenol, 2-methoxy-4-(methoxymethyl)-3-methyl-

There total 2 articles about Phenol, 2-methoxy-4-(methoxymethyl)-3-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 5533-03-9
2-methoxy-4-methoxymethylphenol

: 74-88-4
methyl iodide

: 109685-13-4
4-hydroxy-3-methoxy-2-methylbenzyl methyl ether

Guidance literature:: With n-butyllithium;
DOI:10.1016/S0040-4039(00)85150-3

Reference yield:

: 498-00-0
4-hydroxymethyl-2-methoxyphenol

: 109685-13-4
4-hydroxy-3-methoxy-2-methylbenzyl methyl ether

Guidance literature:: Multi-step reaction with 2 steps

1.1: 27.3 g / p-TSA / methanol / 6 h / 20 °C

2.1: n-BuLi / tetrahydrofuran / 4.25 h / -15 - 0 °C

2.2: tetrahydrofuran; CH₂Cl₂ / -10 °C

With n-butyllithium; toluene-4-sulfonic acid; In tetrahydrofuran; methanol;
DOI:10.1021/ol062067i