Technology Process of C27H26N4O2
There total 5 articles about C27H26N4O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: water / methanol / 50 °C / Alkaline conditions
2: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 20 °C
3: formic acid / 2.5 h / 120 °C
With
formic acid; water; N-ethyl-N,N-diisopropylamine; HATU;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2011.05.075
- Guidance literature:
-
Multi-step reaction with 5 steps
1: hydrogenchloride / 7 h / 65 °C
2: tetrabutyl-ammonium chloride; palladium diacetate; triethylamine; tris-(o-tolyl)phosphine / N,N-dimethyl-formamide / 1 h / Microwave irradiation
3: water / methanol / 50 °C / Alkaline conditions
4: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 20 °C
5: formic acid / 2.5 h / 120 °C
With
hydrogenchloride; formic acid; tetrabutyl-ammonium chloride; water; palladium diacetate; triethylamine; N-ethyl-N,N-diisopropylamine; HATU; tris-(o-tolyl)phosphine;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2011.05.075