phenyl [1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-ylmethyl ether

Base Information

• Chemical Name: phenyl [1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-ylmethyl ether
• CAS No.: 876885-74-4
• Molecular Formula: C₁₀H₈N₄OS
• Molecular Weight: 232.266
• Mol file: 876885-74-4.mol

Synonyms:

Chemical Property of phenyl [1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-ylmethyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenyl [1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-ylmethyl ether

There total 3 articles about phenyl [1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-ylmethyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

formic acid (64-18-6) + (5-phenoxymethyl-[1,3,4]thiadiazol-2-yl)-hydrazine → C10H8N4OS (876885-74-4)

Guidance literature:

at 100 ℃; for 2h;

DOI:10.3987/COM-11-12288

Reference yield:

2-chloro-5-(phenoxymethyl)-1,3,4-thiadiazole (121079-08-1) → C10H8N4OS (876885-74-4)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / 3 h / 80 °C

2: 2 h / 100 °C

With hydrazine hydrate; In ethanol;

DOI:10.3987/COM-11-12288

Reference yield:

5-(phenoxymethyl)-1,3,4-thiadiazol-2-amine (121068-32-4) → C10H8N4OS (876885-74-4)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogenchloride; copper; sodium nitrite / ethanol / 80 °C

2: hydrazine hydrate / ethanol / 3 h / 80 °C

3: 2 h / 100 °C

With hydrogenchloride; copper; hydrazine hydrate; sodium nitrite; In ethanol;

DOI:10.3987/COM-11-12288

upstream raw materials:

formic acid

2-chloro-5-(phenoxymethyl)-1,3,4-thiadiazole

5-(phenoxymethyl)-1,3,4-thiadiazol-2-amine