1,4-Bis(2-hydroxy-3,5-di-tert-butylbenzyl)piperazine, 95%

Base Information

• Chemical Name: 1,4-Bis(2-hydroxy-3,5-di-tert-butylbenzyl)piperazine, 95%
• CAS No.: 110546-20-8
• Molecular Formula: C34H54N2O2
• Molecular Weight: 522.815
• Hs Code.: 2933599590
• Mol file: 110546-20-8.mol

Synonyms:2-((3-(2-hydroxybenzylamino)propylamino)methyl)phenol;N,N-trimethylenediaminebis(o-hydroxybenzylamine);N,N'-Bis(2-hydroxybenzyl)-1,3-diaminopropane;2,2'-[propane-1,3-diylbis(iminomethylene)]bis[phenol];2,2'-[1,3-propanediylbis(iminomethanediyl)]diphenol;bis-N,N'-(2-hydroxybenzyl)-1,3-propanediamine;1,4-bis(2-hydroxy-3,5-di-tert-butylbenzyl)piperazidine;2,2'-[1,3-propanediylbis(iminomethylene)]diphenol;6,6'-(piperazine-1,4-diylbis(methylene))bis(2,4-di-tert-butylphenol);1,4-bis(2-hydroxy-3,5-di-tert-butylbenzyl)-piperazine;Phenol,2,2'-[1,3-propanediylbis(iminomethylene)]bis;N,N'-(bis-o-hydroxybenzyl)-1,3-propanediamine;

Chemical Property of 1,4-Bis(2-hydroxy-3,5-di-tert-butylbenzyl)piperazine, 95%

Chemical Property:

• Melting Point: 236-238 °C
• Boiling Point: 553.0±45.0 °C(Predicted)
• PKA: 11.23±0.48(Predicted)
• PSA: 46.94000
• Density: 1.027±0.06 g/cm3(Predicted)
• LogP: 7.48140

Purity/Quality:

99% ^*data from raw suppliers

2,4-Di-tert-butyl-6-({4-[(3,5-di-tert-butyl-2-hydroxyphenyl)methyl]piperazin-1-yl}methyl)phenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2,4-Di-tert-butyl-6-({4-[(3,5-di-tert-butyl-2-hydroxyphenyl)methyl]piperazin-1-yl}methyl)phenol (CAS# 110546-20-8) is a used as a multidentate ligand in the preparation of zirconium-based catalysts for hydrophosphination reactions of alkenes and heterocumulenes.

Technology Process of 1,4-Bis(2-hydroxy-3,5-di-tert-butylbenzyl)piperazine, 95%

There total 1 articles about 1,4-Bis(2-hydroxy-3,5-di-tert-butylbenzyl)piperazine, 95% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

piperazine (110-85-0) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2,4-di-tert-Butylphenol (96-76-4) → 2,2-[μ-(N,N'-piperazindiyl)dimethyl]-bis(4,6-di-tert-butyl-phenol) (110546-20-8)

Guidance literature:

In ethanol; for 20h; Heating;

DOI:10.1016/j.jorganchem.2008.02.012

Reference yield: 80.0%

2,2-[μ-(N,N'-piperazindiyl)dimethyl]-bis(4,6-di-tert-butyl-phenol) (110546-20-8) + tetrabenzylzirconium(IV) (24356-01-2) → C48H66N2O2Zr(2-)

Guidance literature:

In toluene; at 20 ℃;

DOI:10.1039/c5ra23270h

Reference yield: 21.0%

2,2-[μ-(N,N'-piperazindiyl)dimethyl]-bis(4,6-di-tert-butyl-phenol) (110546-20-8) + phenylacetylene (536-74-3) → 1,4-bis(3-phenylprop-2-yn-1-yl)piperazine (47377-38-8)

Guidance literature:

With N-chloro-succinimide; copper(II) choride dihydrate; sodium hydrogencarbonate; In toluene; at 20 - 110 ℃; for 6h; Inert atmosphere;

DOI:10.1055/s-0032-1316862

upstream raw materials:

piperazine

formaldehyd

2,4-di-tert-Butylphenol

Downstream raw materials:

1,4-bis(3-phenylprop-2-yn-1-yl)piperazine

Refernces

• 1、 Edoka,Okoro,Ugwu. "Synthesis of 1,9-diazaphenoxazine carboxamide derivatives via Buchwald-hartwig amidation protocol". . p. 3463 - 3467. Retrieved 2015.
• 2、 Hancock, Stuart L.,Mahon, Mary F.,Kociok-Kohn, Gabriele,Jones, Matthew D.. "Homopiperazine and piperazine complexes of ZrIV and Hf IV and their application to the ring-opening polymerisation of lactide". experimental part. p. 4596 - 4602. Retrieved 2011/12/01.