Technology Process of C35H37N3O3
There total 13 articles about C35H37N3O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-ethyl-N,N-diisopropylamine; HATU;
In
N,N-dimethyl-formamide;
at 20 ℃;
Inert atmosphere;
DOI:10.1021/jm200279v
- Guidance literature:
-
Multi-step reaction with 7 steps
1: copper(l) iodide / tetrahydrofuran / 2 h / Inert atmosphere
2: water; sodium hydroxide / 2 h / 20 °C
3: copper(I) oxide / acetonitrile / 0.5 h / Inert atmosphere; Reflux
4: diisobutylaluminium hydride / dichloromethane / 1 h / -40 °C / Inert atmosphere
5: sodium tris(acetoxy)borohydride / 1,1-dichloroethane / 20 °C / Inert atmosphere
6: hydrogenchloride / 1,4-dioxane / 20 °C / Inert atmosphere
7: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 20 °C / Inert atmosphere
With
copper(I) oxide; hydrogenchloride; copper(l) iodide; water; sodium tris(acetoxy)borohydride; diisobutylaluminium hydride; N-ethyl-N,N-diisopropylamine; HATU; sodium hydroxide;
In
tetrahydrofuran; 1,4-dioxane; 1,1-dichloroethane; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm200279v
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium tris(acetoxy)borohydride / 1,1-dichloroethane / 20 °C / Inert atmosphere
2: hydrogenchloride / 1,4-dioxane / 20 °C / Inert atmosphere
3: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 20 °C / Inert atmosphere
With
hydrogenchloride; sodium tris(acetoxy)borohydride; N-ethyl-N,N-diisopropylamine; HATU;
In
1,4-dioxane; 1,1-dichloroethane; N,N-dimethyl-formamide;
DOI:10.1021/jm200279v