193537-11-0

Basic information

• Product Name: 1-PIPERIDINECARBOXYLIC ACID, 4-(1-CYANO-2-ETHOXY-2-OXOETHYLIDENE)-, 1,1-DIMETHYLETHYL ESTER
• Synonyms: 1-PIPERIDINECARBOXYLIC ACID, 4-(1-CYANO-2-ETHOXY-2-OXOETHYLIDENE)-, 1,1-DIMETHYLETHYL ESTER;tert-butyl 4-(1-cyano-2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate
• CAS NO: 193537-11-0
• Molecular Formula: C₁₅H₂₂N₂O₄
• Molecular Weight: 294.349
• Mol File: 193537-11-0.mol
• Article Data: 17

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-PIPERIDINECARBOXYLIC ACID, 4-(1-CYANO-2-ETHOXY-2-OXOETHYLIDENE)-, 1,1-DIMETHYLETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PIPERIDINECARBOXYLIC ACID, 4-(1-CYANO-2-ETHOXY-2-OXOETHYLIDENE)-, 1,1-DIMETHYLETHYL ESTER(193537-11-0)
• EPA Substance Registry System: 1-PIPERIDINECARBOXYLIC ACID, 4-(1-CYANO-2-ETHOXY-2-OXOETHYLIDENE)-, 1,1-DIMETHYLETHYL ESTER(193537-11-0)

Safety Data

• Hazardous Substances Data: 193537-11-0(Hazardous Substances Data)

Usage

Class

The compound belongs to the class of organic compounds known as piperidinecarboxylic acids.

Ester derivative

The compound is an ester derivative, indicated by the 1,1-dimethylethyl ester group, which means it has a carbon-oxygen double bond.

Unique chemical structure

The compound has a unique chemical structure, which is related to its properties and uses.

Building block

The compound may be used as a building block in the synthesis of other organic compounds.

Pharmaceutical and chemical industries

The compound is used for various applications in the pharmaceutical and chemical industries.

Upstream product

• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 105-56-6 ethyl 2-cyanoacetate 
• 64-19-7 acetic acid 
• 372-09-8 cyanoacetic acid 

Downstream Products

• 644982-76-3 tert-butyl 4-(3-chlorophenyl)-4-(1-cyano-2-ethoxy-2-oxoethyl)piperidine-1-carboxylate 
• 878130-32-6 4-(cyano-ethoxycarbonyl-methyl)-4-(3-methoxy-phenyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 878130-31-5 4-(cyano-ethoxycarbonyl-methyl)-4-(4-methylsulfanyl-phenyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 644982-19-4 4-(1-cyano-1-ethoxycarbonyl-methyl)-4-phenyl-piperidine-1-carboxylic acid tert-butyl ester 
• 1055923-65-3 tert-butyl 4-(3-chloro-5-fluorophenyl)-4-(1-cyano-2-ethoxy-2-oxoethyl)piperidine-1-carboxylate 
• 716353-05-8 C₃₆H₄₂ClN₅O₃S₂ 
• 716359-88-5 t-butyl endo 4-{2-[(1R,5S)-3-(2-methyl-1H-benzimidazol-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}-4-[3-(methylthio)phenyl]piperidine-1-carboxylate 
• 716359-86-3 t-butyl 4-[3-(methylthio)phenyl]-4-(2-oxoethyl)piperidine-1-carboxylate 
• 716360-12-2 C₁₉H₂₆N₂O₂S 
• 716360-11-1 C₂₀H₂₆N₂O₄S 
• 716353-96-7 C₃₅H₃₇N₃O₃ 
• 716353-03-6 C₃₆H₄₂ClN₅O₃S₂ 
• 716359-81-8 t-butyl endo 4-{2-[(1R,5S)-3-(2-methyl-1H-benzimidazol-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}-4-[4-(methylthio)phenyl]piperidine-1-carboxylate 
• 1309376-06-4 C₃₅H₃₈ClF₂N₅O₃S 

Relevant articles and documents

SALT TYPE AND CRYSTAL TYPE OF 4H-PYRAZOLO [1, 5-ALPHA] BENZIMIDAZOLE COMPOUND AND PREPARATION METHOD AND INTERMEDIATE THEREOF

Disclosed in the present invention are a salt type and crystal type of 4H-pyrazolo[1, 5-alpha]benzimidazole compound and the preparation method and intermediate thereof.

ANALOGUES OF 4H-PYRAZOLO[1,5-a] BENZIMIDAZOLE COMPOUND AS PARP INHIBITORS

Disclosed is a series of analogues of 4H-pyrazolo[1,5-α]benzimidazole compound as PARP inhibitors. In particular, disclosed in the invention is a compound as shown by formula (I) or a pharmaceutically acceptable salt thereof as a PARP inhibitor.

PIPERAZINE DERIVATIVES AS HIV PROTEASE INHIBITORS

The present invention is directed to compounds of Formula I pharmaceutical compositions comprising the same, and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS.