vasicine

Base Information

• Chemical Name: vasicine
• CAS No.: 176200-11-6
• Molecular Formula: C₁₁H₁₂N₂O
• Molecular Weight: 188.229
• Mol file: 176200-11-6.mol

Synonyms:

Chemical Property of vasicine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of vasicine

There total 11 articles about vasicine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

3-Hydroxy-2,3,4,9-tetrahydro-1H-pyrrolo[2,1-b]quinazoline-3a-carboxylic acid tert-butyl ester (139080-84-5,139080-86-7) → vasicine (6159-56-4,176200-11-6)

Guidance literature:

With trifluoroacetic acid; at 40 ℃; for 2h;

DOI:10.1016/0040-4039(91)85059-E

Reference yield:

2-amino-1-benzylamine (4403-69-4) + 3-hydroxyoxolan-2-one (19444-84-9) → vasicine (6159-56-4,176200-11-6)

Guidance literature:

at 200 ℃; Erhitzen unter Stickstoff;

Reference yield:

4-Oxy-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazolin-3-ol → deoxypeganine (495-59-0) + vasicine (6159-56-4,176200-11-6)

Guidance literature:

With hydrogenchloride; zinc; for 7h;

DOI:10.1007/BF00630612

upstream raw materials:

2-amino-1-benzylamine

3-hydroxyoxolan-2-one

3-Hydroxy-2,3,4,9-tetrahydro-1H-pyrrolo[2,1-b]quinazoline-3a-carboxylic acid tert-butyl ester

3-hydroxy-1-(2-nitro-benzyl)-pyrrolidin-2-one

Downstream raw materials:

anthranilic acid

acetic acid

4-Hydroxyquinazoline

vasicine