4-(2,2,3,3-Tetrafluoropropoxy)phenylhydrazine

Base Information

Chemical Name:4-(2,2,3,3-Tetrafluoropropoxy)phenylhydrazine
CAS No.:175691-03-9
Molecular Formula:C₉H₁₀F₄N₂O
Molecular Weight:238.185
Hs Code.:
DSSTox Substance ID:DTXSID001023203

Synonyms:175691-03-9;4-(2,2,3,3-tetrafluoropropoxy)phenylhydrazine;[4-(2,2,3,3-tetrafluoropropoxy)phenyl]hydrazine;DTXSID001023203

Suppliers and Price of 4-(2,2,3,3-Tetrafluoropropoxy)phenylhydrazine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(2,2,3,3-Tetrafluoropropoxy)phenylhydrazine

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:238.07292560
Heavy Atom Count:16
Complexity:208

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1NN)OCC(C(F)F)(F)F

Technology Process of 4-(2,2,3,3-Tetrafluoropropoxy)phenylhydrazine

There total 3 articles about 4-(2,2,3,3-Tetrafluoropropoxy)phenylhydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 175691-03-9
4-(2,2,3,3-tetrafluoropropoxy)phenylhydrazine

Guidance literature:: Multi-step reaction with 3 steps

1: 79 percent / K₂CO₃ / dimethylformamide / 17 h / 100 °C

2: 82 percent / hydrazine hydrate, FeCl₃, activated C / methanol / 70 - 80 °C

3: 1.) NaNO₂, aq. HCl, 2.) SnCl₂, aq. HCl, 3.) NaOH

With hydrogenchloride; sodium hydroxide; iron(III) chloride; potassium carbonate; hydrazine hydrate; tin(ll) chloride; sodium nitrite; In methanol; N,N-dimethyl-formamide;
DOI:10.1248/cpb.44.314

Reference yield:

: 109230-72-0
4-(2,2,3,3-tetrafluoropropoxy)nitrobenzene

: 175691-03-9
4-(2,2,3,3-tetrafluoropropoxy)phenylhydrazine

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / hydrazine hydrate, FeCl₃, activated C / methanol / 70 - 80 °C

2: 1.) NaNO₂, aq. HCl, 2.) SnCl₂, aq. HCl, 3.) NaOH

With hydrogenchloride; sodium hydroxide; iron(III) chloride; hydrazine hydrate; tin(ll) chloride; sodium nitrite; In methanol;
DOI:10.1248/cpb.44.314