109230-72-0

Usage

Uses

1-nitro-4-(2,2,3,3-tetrafluoropropoxy)benzene is a useful reactant and research chemical.

Upstream product

• 100-02-7 4-nitro-phenol 
• 679-87-8 1-iodo-1,1,3-trihydroperfluoropropane 
• 76-37-9 2,2,3,3-tetrafluoropropanol 
• 100-00-5 4-chlorobenzonitrile 

Downstream Products

• 69093-55-6 1-phenoxy-1,1,3-trihydroperfluoropropane 
• 175691-03-9 4-(2,2,3,3-tetrafluoropropoxy)phenylhydrazine 
• 169169-33-9 4-(2,2,3,3-tetrafluoropropoxy)phenylcarbamic acid phenyl ester 
• 1027144-67-7 C₁₀H₁₁F₄N₃O₂ 
• 58761-14-1 4-(2,2,3,3-tetrafluoropropoxy)aniline 

Relevant academic research and scientific papers

Reversible light-operated fluorine-containing azo surfactant and preparation method thereof

The invention discloses a reversibly light-control fluorine-containing azo surfactant and a preparation method thereof, and belongs to the technical field of organic synthesis. The above reversibly light-control fluorine-containing azo surfactant has the structural formula shown in the specification, wherein n is equal to 1, 2 or 3. Fluorine-containing alkyl is imported to serve as a dewatering side to give a priority to the improvement of the performance of the dewatering side of the azo surfactant, the improvement of the performance of the azo surfactant is taken as a basis to prepare the novel fluorine-containing azo surfactant with reversible photoresponse, and the research field of the azoic surfactant is widened.

Properties of liquid crystals and Cu2+ recognition based on Schiff bases

Two series of new Schiff base compounds were synthesized. For Schiff base compounds with a pyridine nitrogen atom in 4-position (7a-e), their supramolecular hydrogen bonding complexes show good liquid crystal properties. However, no liquid crystal property is observed for 8a-e. Results of theoretical calculations demonstrate that it is the intermolecular hydrogen bond of Schiff base compounds (8a-e) that prevents the formation of supramolecular hydrogen bonding. The Schiff base compounds, with terminal alkoxy chains, can recognize Cu2+ selectively with a color change. Nevertheless, others cannot recognize Cu2+.

Fuorinated hydrogen bonding liquid crystals based on Schiff base

Two new Schiff base compounds, tailed by the fluoroalkoxy, were synthesized in a three-step process. Those supramolecular structures constructed by hydrogen bonding show good liquid crystal properties with higher clear points and wider mesomorphic phase ranges than other analogs containing a terminal alkoxy chain. Investigation of the optical textures by polarizing microscopy reveals that terminal fiuorinated substituents convert the nematic phase of supramolecular hydrogen-bonding complexes with terminal alkoxy chains into the smectic A phase of those with terminal fluoroalkoxy chains.

ANTIFUNGAL AGENTS

Compounds of formula (I), and pharmaceutically acceptable salts thereof, may be used in therapy, for example as antifungal agents: (I) wherein: Rl, R2, R3, R4, R5, R6, R7, X and X1 are as defined herein. Certain compounds of formula (I) are also provided. Compounds of formula (T), and agriculturally acceptable salts thereof, may also be used as agricultural fungicides.

Optically active antifungal azoles. VI. Synthesis and antifungal activity of N-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl) propyl]-N′-(4-substituted phenyl)-3(2H,4H)-1,2,4-triazolones and 5(1H,4H)-tetrazolones

A new series of optically active antifungal azoles, N-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl) propyl]-N′-(4-substituted phenyl)-3(2H,4H)-1,2,4-triazolones (1,2) and 5(1H,4H)-tetrazolones (3), were prepared from the triflate derivative of (1S)-1-[(2R)-2-(2,4-difluorophenyl)-2-oxiranyl]ethanol (13) by an SN2 displacement reaction with the union of an azolone (17-19) and subsequent ring-opening reaction with 1H-1,2,4-triazole. The optically active oxiranylethanol 13 was synthesized from methyl (R)-lactate in a stereocontrolled manner. The azolones 1-3 prepared showed potent antifungal activities in vitro and in vivo.