3-(3-(Trifluoromethyl)phenoxy)propanoic acid

Base Information

Chemical Name:3-(3-(Trifluoromethyl)phenoxy)propanoic acid
CAS No.:111140-93-3
Molecular Formula:C10H9F3O3
Molecular Weight:234.175
Hs Code.:
DSSTox Substance ID:DTXSID80553206
Wikidata:Q82433743

Synonyms:111140-93-3;3-(3-(Trifluoromethyl)phenoxy)propanoic acid;3-[3-(TRIFLUOROMETHYL)PHENOXY]PROPANOIC ACID;3-(3-(Trifluoromethyl)phenoxy)propanoicacid;SCHEMBL1451309;DTXSID80553206;AC2941;MFCD09049114;AKOS000133089;3(3-trifluoromethylphenoxy)propionic acid;SY225514;3-(3-trifluoromethylphenoxy)propionic acid;3-(3-Trifluoromethyl-phenoxy)propanoic acid;3-(3-Trifluoromethylphenoxy)-propionic acid;CS-0451149;3-(3-Trifluoromethyl-phenoxy)-propionic acid;A920568;A1-04842

Suppliers and Price of 3-(3-(Trifluoromethyl)phenoxy)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-(3-(Trifluoromethyl)phenoxy)propanoic acid

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:234.05037863
Heavy Atom Count:16
Complexity:240

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)OCCC(=O)O)C(F)(F)F

Technology Process of 3-(3-(Trifluoromethyl)phenoxy)propanoic acid

There total 3 articles about 3-(3-(Trifluoromethyl)phenoxy)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 107-94-8
chloropropionic acid

: 98-17-9
3-Trifluoromethylphenol

: 111140-93-3
3-<3-(trifluoromethyl)phenoxy>propanoic acid

Guidance literature:: With sodium hydroxide; for 1h; Heating; pH 10.0;
DOI:10.1021/jm00396a037

Reference yield:

: 590-92-1
3-Bromopropionic acid

: 98-17-9
3-Trifluoromethylphenol

: 111140-93-3
3-<3-(trifluoromethyl)phenoxy>propanoic acid

Guidance literature:: 3-Bromopropionic acid; 3-Trifluoromethylphenol; With sodium hydroxide; In water; at 0 ℃; for 3.5h; Heating / reflux;

With hydrogenchloride; In water; at 10 ℃; pH=2;

Reference yield:

: 57-57-8
β-Propiolactone

: 98-17-9
3-Trifluoromethylphenol

: 111140-93-3
3-<3-(trifluoromethyl)phenoxy>propanoic acid

Guidance literature:: 3-Trifluoromethylphenol; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

β-Propiolactone; In N,N-dimethyl-formamide; at 20 ℃; for 2.5h;

With hydrogenchloride; In water; N,N-dimethyl-formamide; pH=2; Product distribution / selectivity;