1,4-Di(1,3-dioxan-2-yl)butane

Base Information

Chemical Name:1,4-Di(1,3-dioxan-2-yl)butane
CAS No.:111865-42-0
Molecular Formula:C12H22O4
Molecular Weight:230.304
Hs Code.:
DSSTox Substance ID:DTXSID70549870
Nikkaji Number:J3.554.410K
Wikidata:Q82429045
Mol file:111865-42-0.mol

Synonyms:1,4-di(1,3-dioxan-2-yl)butane;111865-42-0;DTXSID70549870;2,2'-(Butane-1,4-diyl)bis(1,3-dioxane)

Suppliers and Price of 1,4-Di(1,3-dioxan-2-yl)butane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 1,4-Di(1,3-dioxan-2-yl)butane

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:230.15180918
Heavy Atom Count:16
Complexity:154

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC(OC1)CCCCC2OCCCO2

Technology Process of 1,4-Di(1,3-dioxan-2-yl)butane

There total 3 articles about 1,4-Di(1,3-dioxan-2-yl)butane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: (1,3-dioxan-2-yl)ethylmagnesium bromide

: 100-59-4
phenylmagnesium chloride

: 92-52-4,1594-86-1
biphenyl

: 111865-42-0
2-[4-(1,3-dioxan-2-yl)butyl]-1,3-dioxane

: 5663-30-9
2-(2-phenylethyl)-1,3-dioxane

Guidance literature:: (1,3-dioxan-2-yl)ethylmagnesium bromide; phenylmagnesium chloride; With dinitrogen monoxide; In tetrahydrofuran; at 0 ℃; for 0.0833333h; Glovebox; Schlenk technique;

With dilithium tetrachlorocuprate; In tetrahydrofuran; at 0 - 20 ℃; for 18h; Schlenk technique; Glovebox;
DOI:10.1002/anie.201302471

Reference yield:

: (1,3-dioxan-2-yl)ethylmagnesium bromide

: 5702-29-4
2-ethyl-1,3-dioxane

: 111865-42-0
2-[4-(1,3-dioxan-2-yl)butyl]-1,3-dioxane

Guidance literature:: With iron(II) acetate; 1,3-bis(mesityl)imidazolium chloride; In tetrahydrofuran; at 50 - 60 ℃; for 0.333333h; Schlenk technique; Inert atmosphere;
DOI:10.1039/c2sc21754f

Reference yield:

: (1,3-dioxan-2-yl)ethylmagnesium bromide

: 136611-26-2
(S)-4-<(t-butyldiphenylsilyl)oxy>-3-methyl-2-cyclohexenone

: 111865-42-0
2-[4-(1,3-dioxan-2-yl)butyl]-1,3-dioxane

: 184481-12-7
(3S,4S)-4-(tert-Butyl-diphenyl-silanyloxy)-3-(2-[1,3]dioxan-2-yl-ethyl)-3-methyl-cyclohexanone

Guidance literature:: With N,N,N,N,N,N-hexamethylphosphoric triamide; ammonium hydroxide; chloro-trimethyl-silane; copper(I) bromide dimethylsulfide complex; ammonium chloride; Yield given. Multistep reaction; 1.) THF, -78 deg C, 3 h; -78 deg C to -50 deg C, 2.5 h, 2.) H₂O, Et₂O;
DOI:10.1021/jo961605+