Cinacalcet Impurity B

Base Information

Chemical Name:Cinacalcet Impurity B
CAS No.:66469-40-7
Molecular Formula:C₁₉H₁₉N
Molecular Weight:261.367
Hs Code.:

Synonyms:

Suppliers and Price of Cinacalcet Impurity B

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-N-Benzyl-1-(1-naphthyl)ethylamine
10g
$ 1175.00

Biosynth Carbosynth
Cinacalcet impurity B
250 mg
$ 650.00

Biosynth Carbosynth
Cinacalcet impurity B
100 mg
$ 400.00

Biosynth Carbosynth
Cinacalcet impurity B
50 mg
$ 300.00

Biosynth Carbosynth
Cinacalcet impurity B
25 mg
$ 200.00

Biosynth Carbosynth
Cinacalcet impurity B
10 mg
$ 104.00

Total 6 raw suppliers

Chemical Property of Cinacalcet Impurity B

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

(R)-N-Benzyl-1-(1-naphthyl)ethylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses (R)-N-Benzyl-1-(1-naphthyl)ethylamine is formed as a byproduct in the one-pot synthesis of Cinacalcet Hydrochloride (C441800); a calcimimetic agent and calcium-sensing receptor antagonist.

Technology Process of Cinacalcet Impurity B

There total 9 articles about Cinacalcet Impurity B which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 3886-70-2
(R)-1-(1-Naphthyl)ethylamine

: 100-52-7
benzaldehyde

: 66469-40-7,81479-16-5
N‐benzyl‐1‐(1‐naphthyl)ethylamine

Guidance literature:: With sodium tetrahydroborate; iron(III) trifluoromethanesulfonate; In dichloromethane; at 20 ℃; for 0.0833333h;
DOI:10.1016/j.tetlet.2012.06.018

Reference yield: 81.42%

: 154318-44-2
(1R)-1-(1-naphthyl)-N-(phenylmethylene)ethanamine

: 66469-40-7,81479-16-5
N‐benzyl‐1‐(1‐naphthyl)ethylamine

Guidance literature:: (1R)-1-(1-naphthyl)-N-(phenylmethylene)ethanamine; With sodium cyanoborohydride; In ethanol; at 25 - 50 ℃;

With hydrogenchloride; In n-heptane; water; pH=1 - 2;

Reference yield: 52.0%

: 3886-70-2
(R)-1-(1-Naphthyl)ethylamine

: 100-51-6,185532-71-2
benzyl alcohol

: 66469-40-7,81479-16-5
N‐benzyl‐1‐(1‐naphthyl)ethylamine

: 154318-44-2
(1R)-1-(1-naphthyl)-N-(phenylmethylene)ethanamine

Guidance literature:: With 1,4-diaza-bicyclo[2.2.2]octane; [RuCl₂(IiPr)(p-cymene)]; In toluene; for 24h; Inert atmosphere; Molecular sieve; Reflux;
DOI:10.1021/om201095m