Technology Process of 1H-Indol-6-ol, 5-methoxy-, acetate (ester)
There total 9 articles about 1H-Indol-6-ol, 5-methoxy-, acetate (ester) which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 98 percent / 4-(dimethylamino)pyridine / 1 h
2: KF, 18-crown-8 / propan-2-ol / 5 h
3: acetic anhydride, sodium acetate / overnight
4: 1.) H2; 2.) acetic anhydride, 4-(dimethylamino)pyridine / 1.) 5percent Pt/C / 1.) acetic acid, 15 psi, overnight; 2.) room temperature
With
dmap; potassium fluoride; 18-crown-8; hydrogen; sodium acetate; acetic anhydride;
platinum on activated charcoal;
In
isopropyl alcohol;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: CF3COOH / 60 °C
2: 98 percent / 4-(dimethylamino)pyridine / 1 h
3: KF, 18-crown-8 / propan-2-ol / 5 h
4: acetic anhydride, sodium acetate / overnight
5: 1.) H2; 2.) acetic anhydride, 4-(dimethylamino)pyridine / 1.) 5percent Pt/C / 1.) acetic acid, 15 psi, overnight; 2.) room temperature
With
dmap; potassium fluoride; 18-crown-8; hydrogen; sodium acetate; acetic anhydride; trifluoroacetic acid;
platinum on activated charcoal;
In
isopropyl alcohol;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: KF, 18-crown-8 / propan-2-ol / 5 h
2: acetic anhydride, sodium acetate / overnight
3: 1.) H2; 2.) acetic anhydride, 4-(dimethylamino)pyridine / 1.) 5percent Pt/C / 1.) acetic acid, 15 psi, overnight; 2.) room temperature
With
dmap; potassium fluoride; 18-crown-8; hydrogen; sodium acetate; acetic anhydride;
platinum on activated charcoal;
In
isopropyl alcohol;
