1-(Naphthalen-2-yl)-2,2-diphenylethan-1-one

Base Information

• Chemical Name: 1-(Naphthalen-2-yl)-2,2-diphenylethan-1-one
• CAS No.: 113487-88-0
• Molecular Formula: C24H18O
• Molecular Weight: 322.406
• DSSTox Substance ID: DTXSID40552639
• Nikkaji Number: J2.907.036I
• Wikidata: Q82432997
• Mol file: 113487-88-0.mol

Synonyms:113487-88-0;1-(Naphthalen-2-yl)-2,2-diphenylethan-1-one;1-(NAPHTHALEN-2-YL)-2,2-DIPHENYLETHANONE;DTXSID40552639

Chemical Property of 1-(Naphthalen-2-yl)-2,2-diphenylethan-1-one

Chemical Property:

• XLogP3: 6.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 322.135765193
• Heavy Atom Count: 25
• Complexity: 411

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)C3=CC4=CC=CC=C4C=C3

Technology Process of 1-(Naphthalen-2-yl)-2,2-diphenylethan-1-one

There total 3 articles about 1-(Naphthalen-2-yl)-2,2-diphenylethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1-(diphenylmethylidene)-1H-cyclopropa[b]naphthalene (92012-57-2) → 1-(naphthalen-2-yl)-2,2-diphenylethan-1-one (113487-88-0)

Guidance literature:

With trifluorormethanesulfonic acid; In water; acetonitrile; at 50 ℃; for 45h;

DOI:10.1071/CH9871375

Reference yield: 64.0%

bromobenzene (108-86-1,52753-63-6) + methyl 2-naphthyl ketone (93-08-3) → 1-(naphthalen-2-yl)-2,2-diphenylethan-1-one (113487-88-0)

Guidance literature:

With potassium phosphate; tetrabutylammomium bromide; water; palladium diacetate; Diphenylphosphine oxide; In 1,4-dioxane; at 160 ℃; for 24h; Inert atmosphere;

DOI:10.1002/adsc.201701596

Reference yield: 59.0%

β-naphthaldehyde (66-99-9) + Bromodiphenylmethane (776-74-9) → 1-(naphthalen-2-yl)-2,2-diphenylethan-1-one (113487-88-0)

Guidance literature:

With 3-(2,4,6-trimethyl-phenyl)-5,6,7,8-tetrahydro-4H-cycloheptathiazol-3-ium perchlorate; caesium carbonate; In tetrahydrofuran; at 25 ℃; for 3h; Inert atmosphere;

DOI:10.1021/ol102626p

upstream raw materials:

1-(diphenylmethylidene)-1H-cyclopropa[b]naphthalene

β-naphthaldehyde

Bromodiphenylmethane

bromobenzene