Ethanone, 1-(2-naphthalenyl)-2,2-diphenyl-

Base Information

• Chemical Name: Ethanone, 1-(2-naphthalenyl)-2,2-diphenyl-
• CAS No.: 113487-88-0
• Molecular Formula: C24H18O
• Molecular Weight: 322.406
• Mol file: 113487-88-0.mol

Synonyms:

Chemical Property of Ethanone, 1-(2-naphthalenyl)-2,2-diphenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethanone, 1-(2-naphthalenyl)-2,2-diphenyl-

There total 3 articles about Ethanone, 1-(2-naphthalenyl)-2,2-diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1-(diphenylmethylidene)-1H-cyclopropa[b]naphthalene (92012-57-2) → 1-(naphthalen-2-yl)-2,2-diphenylethan-1-one (113487-88-0)

Guidance literature:

With trifluorormethanesulfonic acid; In water; acetonitrile; at 50 ℃; for 45h;

DOI:10.1071/CH9871375

Reference yield: 64.0%

bromobenzene (108-86-1,52753-63-6) + methyl 2-naphthyl ketone (93-08-3) → 1-(naphthalen-2-yl)-2,2-diphenylethan-1-one (113487-88-0)

Guidance literature:

With potassium phosphate; tetrabutylammomium bromide; water; palladium diacetate; Diphenylphosphine oxide; In 1,4-dioxane; at 160 ℃; for 24h; Inert atmosphere;

DOI:10.1002/adsc.201701596

Reference yield: 59.0%

β-naphthaldehyde (66-99-9) + Bromodiphenylmethane (776-74-9) → 1-(naphthalen-2-yl)-2,2-diphenylethan-1-one (113487-88-0)

Guidance literature:

With 3-(2,4,6-trimethyl-phenyl)-5,6,7,8-tetrahydro-4H-cycloheptathiazol-3-ium perchlorate; caesium carbonate; In tetrahydrofuran; at 25 ℃; for 3h; Inert atmosphere;

DOI:10.1021/ol102626p

upstream raw materials:

1-(diphenylmethylidene)-1H-cyclopropa[b]naphthalene

β-naphthaldehyde

Bromodiphenylmethane

bromobenzene

Refernces

• 1、 Padmanaban, Mohan,Biju, Akkattu T.,Glorius, Frank. "N-heterocyclic carbene-catalyzed cross-coupling of aromatic aldehydes with activated alkyl halides". supporting information; experimental part. p. 98 - 101. Retrieved 2011/03/19.