C₁₈H₁₈FN₅O₃

Base Information

Chemical Name:C₁₈H₁₈FN₅O₃
CAS No.:1227917-79-4
Molecular Formula:C₁₈H₁₈FN₅O₃
Molecular Weight:371.371
Hs Code.:

C<sub>18</sub>H<sub>18</sub>FN<sub>5</sub>O<sub>3</sub>

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₈H₁₈FN₅O₃

Chemical Property:

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Technology Process of C₁₈H₁₈FN₅O₃

There total 5 articles about C₁₈H₁₈FN₅O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1227917-77-2
C₁₈H₂₀FN₅O₂

: 1227917-79-4
C₁₈H₁₈FN₅O₃

Guidance literature:: With chromium(VI) oxide; periodic acid; In water; acetonitrile; at 0 - 15 ℃;
DOI:10.1021/jm101527u

Reference yield:

: 10397-15-6
4,6-dichloro-N-methyl-2-pyrimidinamine

: 1227917-79-4
C₁₈H₁₈FN₅O₃

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / acetonitrile / 1 h / 160 °C / Microwave irradiation

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate / 1,4-dioxane; water / 100 - 120 °C / Microwave irradiation

3: chromium(VI) oxide; periodic acid / water; acetonitrile / 0 - 15 °C

With chromium(VI) oxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate; periodic acid; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; water; acetonitrile; 2: Suzuki coupling;
DOI:10.1021/jm101527u

Reference yield:

: 1227911-03-6
[(2S,5R)-5-methyl-2-morpholinyl]methanol hydrochloride

: 1227917-79-4
C₁₈H₁₈FN₅O₃

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / acetonitrile / 1 h / 160 °C / Microwave irradiation

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate / 1,4-dioxane; water / 100 - 120 °C / Microwave irradiation

3: chromium(VI) oxide; periodic acid / water; acetonitrile / 0 - 15 °C

With chromium(VI) oxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate; periodic acid; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; water; acetonitrile; 2: Suzuki coupling;
DOI:10.1021/jm101527u