brackenin hexamethyl ether

Base Information

• Chemical Name: brackenin hexamethyl ether
• CAS No.: 126639-58-5
• Molecular Formula: C₃₆H₃₈O₈
• Molecular Weight: 598.693
• Mol file: 126639-58-5.mol

Synonyms:

Chemical Property of brackenin hexamethyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of brackenin hexamethyl ether

There total 5 articles about brackenin hexamethyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

1,4-bis(2,4-dimethoxyphenyl)butane-1,4-dione (16290-20-3) + p-Methoxybenzyl bromide (2746-25-0) → meso-(2R,3S)-1,4-bis(2,4-dimethoxyphenyl)-2,3-bis(4-methoxybenzyl)butane-1,4-dione (125409-39-4) + (2RS,3RS)-1,4-Bis-(2,4-dimethoxyphenyl)-2,3-bis-(4-methoxybenzyl)butane-1,4-dione (89945-90-4,125409-39-4,125409-40-7,126639-58-5) + 1,4-bis-(2,4-dimethoxy-phenyl)-2,2-bis-(4-methoxy-benzyl)-butane-1,4-dione

Guidance literature:

1,4-bis(2,4-dimethoxyphenyl)butane-1,4-dione; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 1h;

p-Methoxybenzyl bromide; With N,N,N,N,N,N-hexamethylphosphoric triamide; In tetrahydrofuran; at -78 - 20 ℃;

Reference yield:

2',4,4'-trimethoxydihydrochalcone trimethylsilyl enol ether (125304-89-4) → meso-(2R,3S)-1,4-bis(2,4-dimethoxyphenyl)-2,3-bis(4-methoxybenzyl)butane-1,4-dione (125409-39-4) + (2RS,3RS)-1,4-Bis-(2,4-dimethoxyphenyl)-2,3-bis-(4-methoxybenzyl)butane-1,4-dione (89945-90-4,125409-39-4,125409-40-7,126639-58-5)

Guidance literature:

With silver(l) oxide; In dimethyl sulfoxide; at 100 ℃; for 6h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

Reference yield:

dimethyl sulfate (77-78-1) + brackenin (89945-88-0) → brackenin hexamethyl ether (89945-90-4,126639-58-5)

Guidance literature:

With potassium carbonate; In acetone; for 15h; Heating;

DOI:10.1016/S0031-9422(00)97705-7

upstream raw materials:

1,4-bis(2,4-dimethoxyphenyl)butane-1,4-dione

p-Methoxybenzyl bromide

2',4,4'-trimethoxydihydrochalcone trimethylsilyl enol ether

1-(2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)propan-1-one

Downstream raw materials:

2,5-Bis-(2,4-dimethoxy-phenyl)-3,4-bis-(4-methoxy-benzyl)-furan