2',4,4'-trimethoxydihydrochalcone trimethylsilyl enol ether

Base Information

• Chemical Name: 2',4,4'-trimethoxydihydrochalcone trimethylsilyl enol ether
• CAS No.: 125304-89-4
• Molecular Formula: C₂₁H₂₈O₄Si
• Molecular Weight: 372.536
• Mol file: 125304-89-4.mol

Synonyms:2',4,4'-trimethoxydihydrochalcone trimethylsilyl enol ether

Chemical Property of 2',4,4'-trimethoxydihydrochalcone trimethylsilyl enol ether

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2',4,4'-trimethoxydihydrochalcone trimethylsilyl enol ether

There total 1 articles about 2',4,4'-trimethoxydihydrochalcone trimethylsilyl enol ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

chloro-trimethyl-silane (75-77-4) + 1-(2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)propan-1-one (93903-83-4) → 2',4,4'-trimethoxydihydrochalcone trimethylsilyl enol ether (125304-89-4)

Guidance literature:

With 1,8-diazabicycloundec-7-ene; In dichloromethane; Heating; overnight;

Reference yield:

2',4,4'-trimethoxydihydrochalcone trimethylsilyl enol ether (125304-89-4) → meso-(2R,3S)-1,4-bis(2,4-dimethoxyphenyl)-2,3-bis(4-methoxybenzyl)butane-1,4-dione (125409-39-4) + (2RS,3RS)-1,4-Bis-(2,4-dimethoxyphenyl)-2,3-bis-(4-methoxybenzyl)butane-1,4-dione (89945-90-4,125409-39-4,125409-40-7,126639-58-5)

Guidance literature:

With silver(l) oxide; In dimethyl sulfoxide; at 100 ℃; for 6h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

upstream raw materials:

chloro-trimethyl-silane

1-(2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)propan-1-one

Downstream raw materials:

meso-(2R,3S)-1,4-bis(2,4-dimethoxyphenyl)-2,3-bis(4-methoxybenzyl)butane-1,4-dione

(2RS,3RS)-1,4-Bis-(2,4-dimethoxyphenyl)-2,3-bis-(4-methoxybenzyl)butane-1,4-dione