Methyl 2-[6-[(2-methylpropan-2-yl)oxycarbonylamino]pyridin-3-yl]acetate

Base Information

Chemical Name:Methyl 2-[6-[(2-methylpropan-2-yl)oxycarbonylamino]pyridin-3-yl]acetate
CAS No.:1260742-24-2
Molecular Formula:C₁₃H₁₈N₂O₄
Molecular Weight:266.297
Hs Code.:
DSSTox Substance ID:DTXSID201140132
Mol file:1260742-24-2.mol

Synonyms:1260742-24-2;SCHEMBL15701270;DTXSID201140132;3-Pyridineacetic acid, 6-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester

Suppliers and Price of Methyl 2-[6-[(2-methylpropan-2-yl)oxycarbonylamino]pyridin-3-yl]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
(6-tert-Butoxycarbonylamino-pyridin-3-yl)-aceticacidmethylester 95
10g
$ 2933.00

American Custom Chemicals Corporation
(6-TERT-BUTOXYCARBONYLAMINO-PYRIDIN-3-YL)-ACETIC ACID METHYL ESTER 95.00%
5MG
$ 501.59

Total 1 raw suppliers

Chemical Property of Methyl 2-[6-[(2-methylpropan-2-yl)oxycarbonylamino]pyridin-3-yl]acetate

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:266.12665706
Heavy Atom Count:19
Complexity:325

Purity/Quality:: (6-tert-Butoxycarbonylamino-pyridin-3-yl)-aceticacidmethylester 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=NC=C(C=C1)CC(=O)OC

Technology Process of Methyl 2-[6-[(2-methylpropan-2-yl)oxycarbonylamino]pyridin-3-yl]acetate

There total 2 articles about Methyl 2-[6-[(2-methylpropan-2-yl)oxycarbonylamino]pyridin-3-yl]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4248-19-5
tert-butyl carbazate

: 717106-69-9
methyl 2-(6-chloropyridin-3-yl)acetate

: 1260742-24-2
C₁₃H₁₈N₂O₄

Guidance literature:: tert-butyl carbazate; methyl 2-(6-chloropyridin-3-yl)acetate; With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; XPhos; In tetrahydrofuran; for 0.0833333h; Inert atmosphere; Sonication;

In tetrahydrofuran; at 70 ℃; Inert atmosphere; Schlenk technique;

Reference yield:

: 39891-13-9
2-(6-chloropyridin-3-yl)acetic acid

: 1260742-24-2
C₁₃H₁₈N₂O₄

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid / 0.75 h / 20 °C / Inert atmosphere

2.1: caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; XPhos / tetrahydrofuran / 0.08 h / Inert atmosphere; Sonication

2.2: 70 °C / Inert atmosphere; Schlenk technique

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sulfuric acid; caesium carbonate; XPhos; In tetrahydrofuran;