39891-13-9

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloropyridine-5-acetic acid is used as an intermediate in the synthesis of pharmaceuticals for its ability to form heterocyclic compounds, which are essential in the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 2-chloropyridine-5-acetic acid is utilized as an intermediate in the production of various agrochemicals, contributing to the development of effective pesticides and other agricultural chemicals to protect crops and enhance agricultural productivity.
Used in Dye Industry:
2-Chloropyridine-5-acetic acid is also used as an intermediate in the synthesis of dyes, where its ability to form heterocyclic compounds is leveraged to create a wide range of colorants for various applications, including textiles, plastics, and printing inks.

InChI:InChI=1/C7H6ClNO2/c8-6-2-1-5(4-9-6)3-7(10)11/h1-2,4H,3H2,(H,10,11)

Upstream product

• 39891-09-3 (6-chloro-pyridin-3-yl)-acetonitrile 
• 70258-18-3 2-chloro-5-(chloromethyl)pyridine 
• 124-38-9 carbon dioxide 
• 197376-47-9 ethyl (6-chloro-pyridin-3-yl)acetate 
• 53939-30-3 5-bromo-2-chloropyridine 

Downstream Products

• 846548-86-5 (2-chloropyridin-5-yl)acetic acid hydrazide 
• 897016-87-4 2-(6-Chloro-pyridin-3-yl)-N-(3-fluoro-benzyl)-acetamide 
• 920017-49-8 2-phenylpyridine-5-acetic acid 
• 1000668-73-4 2-(3-Chloro-phenyl)-pyridine-5-acetic acid 
• 117528-28-6 2-chloro-5-(2-hydroxyethyl)pyridine 
• 1220279-03-7 2-(6-chloropyridin-3-yl)-N-p-tolylacetamide 
• 1279713-24-4 aqua(tribenzyl)tin(IV) 6-chloro-3-pyridineacetate 
• 1268383-79-4 methyl [2-(2,3-difluorophenyl)-5H-imidazo[4,5-d]pyridazin-5-yl]{6-[4-(propyloxy)-2-(trifluoromethyl)phenyl]-3-pyridinyl}acetate 
• 1268383-80-7 ethyl [2-(2,3-difluorophenyl)-5H-imidazo[4,5-d]pyridazin-5-yl]{6-[4-(propyloxy)-2-(trifluoromethyl)phenyl]-3-pyridinyl}acetate 
• 1268383-82-9 1-methylethyl [2-(2,3-difluorophenyl)-5H-imidazo[4,5-d]pyridazin-5-yl]{6-[4-(propyloxy)-2-(trifluoromethyl)phenyl]-3-pyridinyl}acetate 
• 1268385-53-0 methyl {6-[4-(propyloxy)-2-(trifluoromethyl)phenyl]-3-pyridinyl}acetate 
• 1268385-54-1 methyl bromo{6-[4-(propyloxy)-2-(trifluoromethyl)phenyl]-3-pyridinyl}acetate 
• 54127-64-9 2-chloro-5-aminoethylpyridine 
• 433336-90-4 2-(6-chloropyridin-3-yl)-acetamide 

Relevant academic research and scientific papers

Identification and Profiling of a Novel Diazaspiro[3.4]octane Chemical Series Active against Multiple Stages of the Human Malaria Parasite Plasmodium falciparum and Optimization Efforts

A novel diazaspiro[3.4]octane series was identified from a Plasmodium falciparum whole-cell high-throughput screening campaign. Hits displayed activity against multiple stages of the parasite lifecycle, which together with a novel sp3-rich scaffold provided an attractive starting point for a hit-to-lead medicinal chemistry optimization and biological profiling program. Structure-activity-relationship studies led to the identification of compounds that showed low nanomolar asexual blood-stage activity (50 nM) together with strong gametocyte sterilizing properties that translated to transmission-blocking activity in the standard membrane feeding assay. Mechanistic studies through resistance selection with one of the analogues followed by whole-genome sequencing implicated the P. falciparum cyclic amine resistance locus in the mode of resistance.

Synthetic method of fatty acid containing nitrogen heterocycle

The invention discloses a synthetic method of fatty acid containing nitrogen heterocycle. The synthetic method comprises the following steps: (S1) adding a heterocyclic compound with substitution of chloromethyl groups, a catalyst and a solvent DMF into a reaction kettle; (S2) introducing carbon dioxide to lead the pressure in the kettle to be 2-4MPa, adjusting and reacting for 10-16 hours at thetemperature of 40-50 DEG C; (S3) adding diluted hydrochloric acid into the reaction kettle to carry out acidification, using ethyl acetate for extraction, combining organic phases, carrying out rotaryevaporation to remove liquid, and further carrying out vacuum drying, thus obtaining the fatty acid containing nitrogen heterocycle. The synthetic method disclosed by the invention has the beneficialeffects that a one-pot method is adopted, the raw materials are easy to obtain, price is low, aftertreatment of products is also simpler, the universality for a substrate is also very high, and the promotion and application are easy.

Synthesis and insecticidal activity of some 1,3,4-oxadiazoles derived from 2-chloropyridine-5-acetic acid

The synthesis of a number of 1,3,4-oxadiazoles 6a-e is described. 2-Chloropyridine-5-acetic acid 3 is prepared starting from easily available 2-chloro-5-chloromethylpyridine 1, via 2-chloro-5-cyanomethylpyridine 2. Esterification of 3 with methanol in the

COMPOUNDS USEFUL AS PESTICIDES

Compounds useful to control pests are provided.