(E)-Ethyl 4,4-dimethoxybut-2-enoate

Base Information

Chemical Name:(E)-Ethyl 4,4-dimethoxybut-2-enoate
CAS No.:114736-25-3
Molecular Formula:C₈H₁₄O₄
Molecular Weight:174.197
Hs Code.:
DSSTox Substance ID:DTXSID00552473
Nikkaji Number:J2.099.409F,J1.449.757I
Wikidata:Q72474478
Mol file:114736-25-3.mol

Synonyms:(E)-Ethyl 4,4-dimethoxybut-2-enoate;114736-25-3;ethyl (E)-4,4-dimethoxybut-2-enoate;ETHYL (2E)-4,4-DIMETHOXYBUT-2-ENOATE;2-Butenoic acid, 4,4-dimethoxy-, ethyl ester, (2E)-;(E)-Ethyl4,4-dimethoxybut-2-enoate;2-Butenoic acid, 4,4-dimethoxy-, ethyl ester, (E)-;MFCD06204472;SCHEMBL632676;DTXSID00552473;SIRJFJKWVNTUKV-AATRIKPKSA-N;AKOS006293513;DS-6753;CS-0141403;2-Butenoic acid, 4,4-dimethoxy-, ethyl ester;(E)-4,4-Dimethoxy-but-2-enoic acid ethyl ester;A855337

Suppliers and Price of (E)-Ethyl 4,4-dimethoxybut-2-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(E)-Ethyl4,4-Dimethoxybut-2-enoate
1g
$ 150.00

Medical Isotopes, Inc.
(E)-Ethyl4,4-Dimethoxybut-2-enoate
10 g
$ 2200.00

Crysdot
(E)-Ethyl4,4-dimethoxybut-2-enoate 95+%
1g
$ 89.00

Crysdot
(E)-Ethyl4,4-dimethoxybut-2-enoate 95+%
10g
$ 475.00

Crysdot
(E)-Ethyl4,4-dimethoxybut-2-enoate 95+%
5g
$ 277.00

American Custom Chemicals Corporation
(E)-ETHYL 4,4-DIMETHOXYBUT-2-ENOATE 95.00%
5MG
$ 503.82

Ambeed
(E)-Ethyl4,4-dimethoxybut-2-enoate 95%
25g
$ 247.00

Ambeed
(E)-Ethyl4,4-dimethoxybut-2-enoate 95%
10g
$ 140.00

Ambeed
(E)-Ethyl4,4-dimethoxybut-2-enoate 95%
5g
$ 95.00

Ambeed
(E)-Ethyl4,4-dimethoxybut-2-enoate 95%
1g
$ 30.00

Total 53 raw suppliers

Chemical Property of (E)-Ethyl 4,4-dimethoxybut-2-enoate

Chemical Property:

Boiling Point:222℃
Flash Point:88℃
PSA：44.76000
Density:1.019
LogP:0.72460
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly)
XLogP3:0.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:174.08920892
Heavy Atom Count:12
Complexity:149

Purity/Quality:

97% ^*data from raw suppliers

(E)-Ethyl4,4-Dimethoxybut-2-enoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C=CC(OC)OC
Isomeric SMILES:CCOC(=O)/C=C/C(OC)OC
Uses (E)-Ethyl 4,4-Dimethoxybut-2-enoate has been used as a reactant for the synthesis of N-substituted-1,2,3,6-tetrahydro-pyridine-4-carbaldehyde, a precursor for synthesizing Aricept.

Technology Process of (E)-Ethyl 4,4-dimethoxybut-2-enoate

There total 3 articles about (E)-Ethyl 4,4-dimethoxybut-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 867-13-0
diethoxyphosphoryl-acetic acid ethyl ester

: 51673-84-8
dimethoxyacetaldehyde

: 19255-60-8,114736-26-4,114736-25-3
(E)-4,4-dimethoxy-but-2-enoic acid ethyl ester

Guidance literature:: With potassium carbonate; In water; toluene; for 2h; optical yield given as %de; Reflux;
DOI:10.1039/c2cc33309k

Reference yield: 82.0%

: 64-17-5
ethanol

: 18778-96-6,4093-49-6
(2E)-4,4-dimethoxybut-2-enal

: 19255-60-8,114736-26-4,114736-25-3
(E)-4,4-dimethoxy-but-2-enoic acid ethyl ester

Guidance literature:: With manganese(IV) oxide; sodium cyanide; acetic acid; at 20 ℃; for 24h;

Reference yield:

: 867-13-0
diethoxyphosphoryl-acetic acid ethyl ester

: 51673-84-8
dimethoxyacetaldehyde

: 114736-26-4
(Z)-4,4-Dimethoxy-but-2-enoic acid ethyl ester

: 19255-60-8,114736-26-4,114736-25-3
(E)-4,4-dimethoxy-but-2-enoic acid ethyl ester

Guidance literature:: With potassium carbonate; In cyclohexane; Yield given. Yields of byproduct given; Heating;
DOI:10.1016/S0040-4039(00)96713-3