Technology Process of 1,3-Propanediol, 1-phenyl-, 3-methanesulfonate, (1R)-
There total 6 articles about 1,3-Propanediol, 1-phenyl-, 3-methanesulfonate, (1R)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 90 percent / H2 / RuBr2((S)-(6,6'-(MeO)2-biphenyl-2,2'-diyl)bis(Ph2-phosphane) / ethanol / 18 h / 50 °C / 760.05 Torr
2: 86 percent / LiAlH4 / tetrahydrofuran; diethyl ether / 1.5 h / 0 - 20 °C
3: 82 percent / Et3N / diethyl ether / 3 h / -10 - 0 °C
With
lithium aluminium tetrahydride; hydrogen; triethylamine;
(S)-BinapRuBr2;
In
tetrahydrofuran; diethyl ether; ethanol;
DOI:10.1002/adsc.200390021
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 92 percent / LiAlH4 / tetrahydrofuran / 1 h / 20 °C
2: 85 percent / Et3N / diethyl ether / 3 h / -10 - 0 °C / cooling
With
lithium aluminium tetrahydride; triethylamine;
In
tetrahydrofuran; diethyl ether;
DOI:10.1016/j.tet.2004.12.059
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 98 percent / sodium bis(2-methoxyethoxy)aluminum hydride (Red-Al) / 1,2-dimethoxy-ethane; toluene / 3 h / Ambient temperature
2: 74 percent / triethylamine / diethyl ether / 3 h / -10 - 0 °C
With
triethylamine; sodium bis(2-methoxyethoxy)aluminium dihydride;
In
1,2-dimethoxyethane; diethyl ether; toluene;
DOI:10.1021/jo00252a036