2-Oxetanol, 3,3-difluoro-4-phenyl-2-(trifluoromethyl)-

Base Information

Chemical Name:2-Oxetanol, 3,3-difluoro-4-phenyl-2-(trifluoromethyl)-
CAS No.:116020-01-0
Molecular Formula:C10H7F5O2
Molecular Weight:254.156
Hs Code.:
DSSTox Substance ID:DTXSID00468904
Mol file:116020-01-0.mol

Synonyms:116020-01-0;2-Oxetanol, 3,3-difluoro-4-phenyl-2-(trifluoromethyl)-;DTXSID00468904

Suppliers and Price of 2-Oxetanol, 3,3-difluoro-4-phenyl-2-(trifluoromethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-Oxetanol, 3,3-difluoro-4-phenyl-2-(trifluoromethyl)-

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:1
Exact Mass:254.03662027
Heavy Atom Count:17
Complexity:298

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2C(C(O2)(C(F)(F)F)O)(F)F

Technology Process of 2-Oxetanol, 3,3-difluoro-4-phenyl-2-(trifluoromethyl)-

There total 2 articles about 2-Oxetanol, 3,3-difluoro-4-phenyl-2-(trifluoromethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 116019-90-0
Lithium-1,1,3,3,3-pentafluorpropenolat

: 100-52-7
benzaldehyde

: 116020-01-0
4-hydroxy-1,1,1,3,3-pentafluoro-4-phenylbutan-2-one hemiacetal

Guidance literature:: In tetrahydrofuran; at 0 ℃;
DOI:10.1016/S0040-4039(00)80432-3

Reference yield:

: 920-66-1
1,1,1,3',3',3'-hexafluoro-propanol

: 100-52-7
benzaldehyde

: 4-hydroxy-1,1,1,3,3-pentafluoro-4-phenylbutan-2-one hydrate

: 116020-01-0
4-hydroxy-1,1,1,3,3-pentafluoro-4-phenylbutan-2-one hemiacetal

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; at 20 ℃; for 17h; Title compound not separated from byproducts;
DOI:10.1021/jo0518856