O-(Methylsulfonyl)-N-(triphenylmethyl)-D-serine methyl ester

Base Information

Chemical Name:O-(Methylsulfonyl)-N-(triphenylmethyl)-D-serine methyl ester
CAS No.:116457-92-2
Molecular Formula:C24H25NO5S
Molecular Weight:439.532
Hs Code.:
DSSTox Substance ID:DTXSID101185107
Mol file:116457-92-2.mol

Synonyms:SCHEMBL25216948;DTXSID101185107;O-(Methylsulfonyl)-N-(triphenylmethyl)-D-serine methyl ester;116457-92-2

Suppliers and Price of O-(Methylsulfonyl)-N-(triphenylmethyl)-D-serine methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of O-(Methylsulfonyl)-N-(triphenylmethyl)-D-serine methyl ester

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:10
Exact Mass:439.14534407
Heavy Atom Count:31
Complexity:610

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C(COS(=O)(=O)C)NC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3
Isomeric SMILES:COC(=O)[C@@H](COS(=O)(=O)C)NC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of O-(Methylsulfonyl)-N-(triphenylmethyl)-D-serine methyl ester

There total 3 articles about O-(Methylsulfonyl)-N-(triphenylmethyl)-D-serine methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 116457-91-1
(2R)-3-hydroxy-2-(tritylamino)propanoic acid methyl ester

: 124-63-0
methanesulfonyl chloride

: 116457-92-2
O-mesyl-N-trityl-D-serine methyl ester

Guidance literature:: With triethylamine; In dichloromethane; at -10 - -5 ℃; for 1.5h; Temperature; Time;

Reference yield:

: 76-83-5
trityl chloride

: 116457-92-2
O-mesyl-N-trityl-D-serine methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / Et₃N / CHCl₃ / 24 h

2: 91 percent / triethylamine / CHCl₃

With triethylamine; In chloroform;
DOI:10.1016/0040-4039(88)80008-X

Reference yield:

: 76-83-5
trityl chloride

: 116457-92-2
O-mesyl-N-trityl-D-serine methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: NEt₃ / CHCl₃

2: NEt₃, DMAP / CHCl₃

With dmap; triethylamine; In chloroform;